Upcoming Seminars

CRC1366 / ECAS InSight

for complete schedule 2020 press here

Anna Jauch

Gèraud Group


PD Dr. Walter Muranyi

Schroten Group

Wednesday, March 4, 2020


CRC1366 / ECAS Seminars in Angioscience

for complete schedule 2020 press here

Prof. Dr. David Jackson

Radcliffe Department of Medicine, Oxford, UK

Thursday, Feb. 13, 2020




Vascular Mini Symposium

April 15th, 2020 at the MPI for Heart and Lung Research, Bad Nauheim

Info and free registration

1st Joint Summer School and Consortium Meeting

June 22-24, 2020 at Pfalzhotel Asselheim

registration Summer School/Consortium Meeting



Hasan* SS, Prinz* A, Jabs M, Taylor J et al.

Endothelial Notch signaling controls insulin transport in muscle.

EMBO Mol Med. in press

Klose R, Prinz A, Tetzlaff F, Weis EM et al.

Loss of the serine protease HTRA1 impairs smooth muscle cells maturation.

Scientific Reports. Dec 3, 2019


Park H, Yamamoto H, Mohn L et al.

Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy

Nat Commun. 2019, November 20

for more


The extended role of blood vessels

Blood vessels form a systemically disseminated organ that distributes oxygen and nutrients and re­moves metabolic waste products. A dense network of microvessels facilitates the trafficking of immune cells throughout the body. Yet, blood vessels do not just support rheological functions. They form one of the body’s largest surfaces serving as critical interface between the circulation and the different organ environments.


Work pursued in the last couple of years has identified critical gatekeeper functions of tissue homeostasis and adaptation to pathologic challenge. It is now increasingly recognized that vascular control of the tissue microenvironment is indispensable in development, homeostasis, inflammation, and metabolism as well as cancer and metastasis. This multitude of vascular functions is mediated by organ-specifically differentiated endothelial and mural cells, whose cellular and molecular heterogeneity has long been recognized.


Yet, distinct organotypic functional attributes as well as the molecular mechanisms controlling endothelial and mural cell differentiation and vascular bed-specific functions have only recently been uncovered. The Collaborative Research Center (CRC) 1366 “Vas­cular Control of Organ Function” aims at systematically studying gatekeeper functions of organotypically differentiated endothelial and mural cells during develop­ment and regeneration.













Prof. Dr. Hellmut G. Augustin

European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University and DKFZ, Heidelberg











Vice Spokesperson

Prof. Dr. Sergij Goerdt

University Hospital for Dermatology,

Venereology and Allergology and European Center for Angioscience (ECAS) University Medical Centre Mannheim

Heidelberg University

News and Upcoming Events


for complete schedule 2020 press here

Anna Jauch

Role of Lyve-1 during hepatic metastasis of malignant


Gèraud group


PD Dr. Walter Muranyi

A human in vitro model of the blood-cerebrospinal

fluid barrier to study endo-epithelial as well as

host-pathogen interaction

Schroten group

Wednesday, March 4, 2020, Tridomus House B, Room 41, Ebene 2

CRC1366/ECAS Seminars in Angioscience

for complete schedule 2020 press here

Prof. Dr. David Jackson

Leucocyte migration in the lymphatics - The importance

of sugar coating

Radcliffe Department of Medicine, University of Oxford, UK

Thursday, February 13, 2020, 4 pm

Alte Brauerei H02, Röntgenstr. 7, Mannheim

Carmen Ruiz de Almodóvar receives ERC Consolidator Grant

 Press release Medical Faculty Mannheim University Heidelberg Dec. 10, 2019

Andreas Fischer receives Gábor Szász Award

Press release German Cancer Research Center (DKFZ), Oct. 7, 2019


Überlebensstrategien im Klub K: Ein bisschen Maß muss sein

Zeitungsartikel der Rhein-Neckar Zeitung vom 13. Juli 2019

for more


Blutgefäße spielen bei einer Krebserkrankung eine wichtige Rolle: Sie ermöglichen es den Tumoren, zu wachsen und sich im Körper auszubreiten

Pressemitteilung des Deutschen Krebsforschungszentrums (DKFZ)


Bericht im Mannheimer Morgen vom 1. März 2019

Pressemitteilung zum Kickoff Meeting


Michael Platten receives the German Cancer Award 2019

Bericht im Mannheimer Morgen vom 2. März 2019


Pressemitteilung vom 23.11.2018

Grünes Licht für neuen gefäßbiologischen Sonderforschungsbereich

Die Deutsche Forschungsgemeinschaft (DFG) fördert die Erforschung von Mechanismen, mit denen Blutgefäße die Funktion von Organen während der Entwicklung und bei Krankheitsprozessen steuern, mit mehr als 11 Mio. Euro.


European Center for Angioscience

Medical Faculty Mannheim
Heidelberg University
Ludolf-Krehl-Straße 13-17
D-68167 Mannheim

Phone +49 621/383-71450