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Upcoming Seminars

CRC1366 / ECAS InSight

for complete schedule 2021 press here

Dr. Ashik Ahmed Abdul Pari

Augustin Group

and

Dr. Katharina Schlereth

Group Leader

Wednesday, October 6, 2021

more

CRC1366 / ECAS Seminars in Angioscience

Prof. Georg Gasteiger

Julius-Maximilians-Universität Würzburg, Germany

Thursday, October 14, 2021

more

EVBO Seminar Series 2021

Thursday, October 7, 2021,

15:00-16:00 (GMT+02:00)

registration and more

Events

 

 

 

 

 

 

 

 

 

 

 

3rd Joint Summer School and Consortium Meeting 2022 (intern)

January 19-21, 2022, Asselheim

Publications

Singhal M*, Gengenbacher N*, Abdul Pari AA* et al.

Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis.

Sci. Transl. Med. 2021 September 1.

Stojanovic A, Cerwenka A

An intimate encounter: DC3s empower anti-tumor CTLs.

Cancer Cell. 2021 August 19.

Luck R, Karakatsani A, Shah B et al.

The angiopoietin-Tie2 pathway re-gulates Purkinje cell dendritic morphogenesis in a cell-autonom-ous manner. 

Cell reports. 2021 August 17.

Kappert L, Ruzicka P, Kutikhin A et al.

Loss of Nfat5 promotes lipid accumulation in vascular smooth muscle cells.

FASEB J. 2021 August 12.

more

The extended role of blood vessels

Blood vessels form a systemically disseminated organ that distributes oxygen and nutrients and re­moves metabolic waste products. A dense network of microvessels facilitates the trafficking of immune cells throughout the body. Yet, blood vessels do not just support rheological functions. They form one of the body’s largest surfaces serving as critical interface between the circulation and the different organ environments.

 

Work pursued in the last couple of years has identified critical gatekeeper functions of tissue homeostasis and adaptation to pathologic challenge. It is now increasingly recognized that vascular control of the tissue microenvironment is indispensable in development, homeostasis, inflammation, and metabolism as well as cancer and metastasis. This multitude of vascular functions is mediated by organ-specifically differentiated endothelial and mural cells, whose cellular and molecular heterogeneity has long been recognized.

 

Yet, distinct organotypic functional attributes as well as the molecular mechanisms controlling endothelial and mural cell differentiation and vascular bed-specific functions have only recently been uncovered. The Collaborative Research Center (CRC) 1366 “Vas­cular Control of Organ Function” aims at systematically studying gatekeeper functions of organotypically differentiated endothelial and mural cells during develop­ment and regeneration.

News and Upcoming Events

CRC1366/ECAS InSight

for complete schedule 2021 press here

Dr. Ashik Ahmed Abdul Pari

Vascular aging limits metastasis

Augustin Group

and

Dr. Katharina Schlereth

TBA

Group Leader

Wednesday, October 6, 2021

CRC1366/ECAS Seminars in Angioscience

Prof. Georg Gasteiger

TBA

IJulius-Maximilians-Universität Würzburg, Germany

Thursday, October 14, 2021

ONLINE via Cisco Webex Meetings

EVBO Seminars Series 2021

Short talk

Claudia Monaco, The Kennedy Institute of Rheumatology, UK

Myeloid cell heterogeneity in atherosclerosis:

one cell at a time

Young Investigator Spotlight (YIS)

Mark Richards, Uppsala University, Sweden

Patterning and regulation of the blood endothelial

cell barrier

Plenary lecture

Martin Schwartz, Yale School of Medicine, USA

How shear stress activates the atheroprotective

transcription factor Klf2

Thursday, October 7, 2021, 15:00-16:00 European Summer Time (GMT+02:00)

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Contact

 

 

 

 

 

 

 

 

 

 

Spokesperson

Prof. Dr. Hellmut G. Augustin

European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University and DKFZ, Heidelberg

 

 

 

 

 

 

 

 

 

Vice Spokesperson

Prof. Dr. Sergij Goerdt

University Hospital for Dermatology,

Venereology and Allergology and European Center for Angioscience (ECAS) University Medical Centre Mannheim

Heidelberg University

Steering Committee 

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Prof. Dr. Ralf Adams

Max Planck Institute for Molecular Biomedicine, Münster
Department of Tissue Morphogenesis

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Prof. Dr. Stefanie Dimmeler

Institute of Cardiovascular Regeneration

Goethe University, Frankfurt

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Prof. Dr. Jörg Heineke

Dept. of Cardiovascular Research, European Center for Angioscience (ECAS),

Medical Faculty Mannheim, Heidelberg University

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Prof. Dr. Carmen Ruiz de Almodóvar

European Center for Angioscience (ECAS)
Faculty of Medicine Mannheim, Heidelberg University

Mahak Singhal receives the Helmholtz Doctoral Prize 2020

Press release Medical Faculty Mannheim University Heidelberg, May 2021

Didier Stainier receives ERC Advanced Grant

Max Planck Institute for Heart and Lung Research, Bad Nauheim, April 2021

Cyrill Géraud receives "Paul Langerhans-Pize" 2021

Press release Medical Faculty Mannheim University Heidelberg, April 2021

Sofia-Iris Bibli receives "Emmy Noether Grant" and "Oskar-Lapp-Prize"

Institute of Vascular Signaling, Center for Molecular Medicine, Goethe University Frankfurt, April 2021

Ralf Adams receives „Feldberg Prize“ 2021

 Press release Max Planck Institute for Molecular Biomedicine, Münster, February 01, 2021

Blood vessels control organ function and disease processes

Press release Medical Faculty Mannheim University Heidelberg, December 04,2020

Lymphatics prevent spreading of cancer cells

Press release German Cancer Research Center (DKFZ), October 26, 2020 

Endothelial cell-specific factor protects metastatic tumor cells

Press release German Cancer Research Center (DKFZ), May 26, 2020 

HIF-1α decelerates natural Killer cells

Press release Medical Faculty Mannheim University Heidelberg May 22, 2020

Prevent metastasis - an antibody with potential

Press release German Cancer Research Center (DKFZ), April 24, 2020 

The role of blood vessels in insulin resistance

Press release German Cancer Research Center (DKFZ), March 27, 2020 

Carmen Ruiz de Almodóvar receives ERC Consolidator Grant

 Press release Medical Faculty Mannheim University Heidelberg Dec. 10, 2019

Andreas Fischer receives Gábor Szász Award

Press release German Cancer Research Center (DKFZ), Oct. 7, 2019

 

Überlebensstrategien im Klub K: Ein bisschen Maß muss sein

Zeitungsartikel der Rhein-Neckar Zeitung vom 13. Juli 2019

for more

 

Blutgefäße spielen bei einer Krebserkrankung eine wichtige Rolle: Sie ermöglichen es den Tumoren, zu wachsen und sich im Körper auszubreiten

Pressemitteilung des Deutschen Krebsforschungszentrums (DKFZ)

 

Bericht im Mannheimer Morgen vom 1. März 2019

Pressemitteilung zum Kickoff Meeting

 

Michael Platten receives the German Cancer Award 2019

Bericht im Mannheimer Morgen vom 2. März 2019

 

Pressemitteilung vom 23.11.2018

Grünes Licht für neuen gefäßbiologischen Sonderforschungsbereich

Die Deutsche Forschungsgemeinschaft (DFG) fördert die Erforschung von Mechanismen, mit denen Blutgefäße die Funktion von Organen während der Entwicklung und bei Krankheitsprozessen steuern, mit mehr als 11 Mio. Euro.

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