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Upcoming Seminars

CRC1366 / ECAS InSight

for complete schedule 2020 press here

Dr. Katharina Schlereth

Augustin Group

and

Sarah Wahby

Michel Group

Wednesday, October 7, 2020

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CRC1366 / ECAS Seminars in Angioscience

for complete schedule 2020 press here

 

Prof. Dr. Stefanie Dimmeler

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Thursday, July 16, 2020

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Events

2nd Joint Summer School and Consortium Meeting

April 21-23, 2021

Publications

Shen Y, Wang X, Lu J et al.

Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer

Cancer Cell. 2020 June 8

Ni J*, Wang X*, Stojanovic A* et al.

Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity.

Immunity. 2020 May 22

 

Singhal M*, Gengenbacher N*, La Porta S* et al.

Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody..

EMBO Mol Med. 2020 April 17

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The extended role of blood vessels

Contact

 

 

 

 

 

 

 

 

 

 

Spokesperson

Prof. Dr. Hellmut G. Augustin

European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University and DKFZ, Heidelberg

 

 

 

 

 

 

 

 

 

 

Vice Spokesperson

Prof. Dr. Sergij Goerdt

University Hospital for Dermatology,

Venereology and Allergology and European Center for Angioscience (ECAS) University Medical Centre Mannheim

Heidelberg University

Blood vessels form a systemically disseminated organ that distributes oxygen and nutrients and re­moves metabolic waste products. A dense network of microvessels facilitates the trafficking of immune cells throughout the body. Yet, blood vessels do not just support rheological functions. They form one of the body’s largest surfaces serving as critical interface between the circulation and the different organ environments.

 

Work pursued in the last couple of years has identified critical gatekeeper functions of tissue homeostasis and adaptation to pathologic challenge. It is now increasingly recognized that vascular control of the tissue microenvironment is indispensable in development, homeostasis, inflammation, and metabolism as well as cancer and metastasis. This multitude of vascular functions is mediated by organ-specifically differentiated endothelial and mural cells, whose cellular and molecular heterogeneity has long been recognized.

 

Yet, distinct organotypic functional attributes as well as the molecular mechanisms controlling endothelial and mural cell differentiation and vascular bed-specific functions have only recently been uncovered. The Collaborative Research Center (CRC) 1366 “Vas­cular Control of Organ Function” aims at systematically studying gatekeeper functions of organotypically differentiated endothelial and mural cells during develop­ment and regeneration.

Steering Committee 

News and Upcoming Events

CRC1366/ECAS InSIGHT

for complete schedule 2020 press here

Dr. Katharina Schlereth

TBA

Augustin group

and

Sarah Wahby

TBA

Michel group

Wednesday, October 7, 2020

ONLINE via Cisco Webex Meetings

CRC1366/ECAS Seminars in Angioscience

for complete schedule 2020 press here

Prof. Dr. Stefanie Dimmeler

Novel insights into endothelial plasticity and signaling

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Thursday, July 9, 2020, 4 pm

ONLINE via Cisco Webex Meetings

Carmen Ruiz de Almodóvar receives ERC Consolidator Grant

 Press release Medical Faculty Mannheim University Heidelberg Dec. 10, 2019

Andreas Fischer receives Gábor Szász Award

Press release German Cancer Research Center (DKFZ), Oct. 7, 2019

 

Überlebensstrategien im Klub K: Ein bisschen Maß muss sein

Zeitungsartikel der Rhein-Neckar Zeitung vom 13. Juli 2019

for more

 

Blutgefäße spielen bei einer Krebserkrankung eine wichtige Rolle: Sie ermöglichen es den Tumoren, zu wachsen und sich im Körper auszubreiten

Pressemitteilung des Deutschen Krebsforschungszentrums (DKFZ)

 

Bericht im Mannheimer Morgen vom 1. März 2019

Pressemitteilung zum Kickoff Meeting

 

Michael Platten receives the German Cancer Award 2019

Bericht im Mannheimer Morgen vom 2. März 2019

 

Pressemitteilung vom 23.11.2018

Grünes Licht für neuen gefäßbiologischen Sonderforschungsbereich

Die Deutsche Forschungsgemeinschaft (DFG) fördert die Erforschung von Mechanismen, mit denen Blutgefäße die Funktion von Organen während der Entwicklung und bei Krankheitsprozessen steuern, mit mehr als 11 Mio. Euro.

Prof. Dr. Ralf Adams

Max Planck Institute for Molecular Biomedicine, Münster
Department of Tissue Morphogenesis

Prof. Dr. Stefanie Dimmeler

Institute of Cardiovascular Regeneration

Goethe University, Frankfurt

Prof. Dr. Jörg Heineke

Dept. of Cardiovascular Research, European Center for Angioscience (ECAS),

Medical Faculty Mannheim, Heidelberg University

Prof. Dr. Carmen Ruiz de Almodóvar

European Center for Angioscience (ECAS)
Institute for Transfusion Medicine/Immunology
Faculty of Medicine Mannheim, Heidelberg University

CRC1366

European Center for Angioscience

Medical Faculty Mannheim
Heidelberg University

Ludolf-Krehl-Straße 13-17
D-68167 Mannheim

Phone +49 621/383-71450