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Upcoming Seminars

CRC1366 / ECAS InSight

for complete schedule 2020 press here

Dr. Hebatullah Laban

Korff Group

and

Jihong Lin

Hammes Group

Wednesday, December 2, 2020

more

CRC1366 / ECAS Seminars in Angioscience

for complete schedule 2020 press here

Dr. Boris Strilic

Max Planck Institute for Heart and Lung Research, Bad Nauheim

Thursday, December 10, 2020

more

Events

NEW:

EVBO Seminar Series 2020/21

Tuesday, December 2, 2020

registration and more

 

2. Joint Summer School and Consortium Meeting

April 21-23, 2021, Best Western Plus - Plaza Hotel Darmstadt

1. CRC1366 International Meeting on 'Vascular Control of Organ Function'

June 28-30, 2021, DKFZ, Heidelberg

Publications

Di Marco B, Crouch EE, Shah B et al.

Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon.

Cell Rep. 2020 Oct 13

Gengenbacher N*, Singhal M*, Mogler C et al.

Timed Ang2-targeted therapy 1 identifies the Angiopoietin-Tie pathway as key regulator of fatal lymphogenous metastasis.

Cancer Discovery. 2020 October 26

Winkler M*, Staniczek T*, Kürschner SW*, Schmid CD* et al.

Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling.

J Hepatol. 2020 September 9

more

The extended role of blood vessels

Blood vessels form a systemically disseminated organ that distributes oxygen and nutrients and re­moves metabolic waste products. A dense network of microvessels facilitates the trafficking of immune cells throughout the body. Yet, blood vessels do not just support rheological functions. They form one of the body’s largest surfaces serving as critical interface between the circulation and the different organ environments.

 

Work pursued in the last couple of years has identified critical gatekeeper functions of tissue homeostasis and adaptation to pathologic challenge. It is now increasingly recognized that vascular control of the tissue microenvironment is indispensable in development, homeostasis, inflammation, and metabolism as well as cancer and metastasis. This multitude of vascular functions is mediated by organ-specifically differentiated endothelial and mural cells, whose cellular and molecular heterogeneity has long been recognized.

 

Yet, distinct organotypic functional attributes as well as the molecular mechanisms controlling endothelial and mural cell differentiation and vascular bed-specific functions have only recently been uncovered. The Collaborative Research Center (CRC) 1366 “Vas­cular Control of Organ Function” aims at systematically studying gatekeeper functions of organotypically differentiated endothelial and mural cells during develop­ment and regeneration.

News and Upcoming Events

CRC1366/ECAS InSIGHT

for complete schedule 2020 press here

Dr. Hebatullah Laban

Endothelial NFAT5-dependent control of lung hypoxia

responses

Korff Group

and

Jihong Lin

microRNA-124a prevents retinal vasoregression in

PKD rats

Hammes Group

Wednesday, December 2, 2020

ONLINE via Cisco Webex Meetings

CRC1366/ECAS Seminars in Angioscience

for complete schedule 2020 press here

Dr. Boris Strilic

The role of endothelial cells in tumor metastasis

Max Planck Institute for Heart and Lung Research, Bad Nauheim

Thursday, December 10, 2020, 4 pm

ONLINE via Cisco Webex Meetings

EVBO Seminars Series 2020

Short talk

Guido de Meyer, University of Antwerp, Belgium

‘Partial inhibition of glycolysis reduces atherogenesis

independent of intraplaque neovascularization in mice’

Young Investigator Spotlight (YIS)

Sandro Da Mesquita, University of Virginia, USA

‘Untangling the role of meningeal lymphatic drainage in

Alzheimer's disease’

Plenary lecture

Karina Yaniv, Weizmann Institute, Israel

‘Is lymphatic cell differentiation a one-way ticket?’

 

Tuesday, December 2, 2020, 15:00-16:00 European Winter Time (GMT+01:00)

Contact

 

 

 

 

 

 

 

 

 

 

Spokesperson

Prof. Dr. Hellmut G. Augustin

European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University and DKFZ, Heidelberg

 

 

 

 

 

 

 

 

 

 

Vice Spokesperson

Prof. Dr. Sergij Goerdt

University Hospital for Dermatology,

Venereology and Allergology and European Center for Angioscience (ECAS) University Medical Centre Mannheim

Heidelberg University

Steering Committee 

Prof. Dr. Ralf Adams

Max Planck Institute for Molecular Biomedicine, Münster
Department of Tissue Morphogenesis

Prof. Dr. Stefanie Dimmeler

Institute of Cardiovascular Regeneration

Goethe University, Frankfurt

Prof. Dr. Jörg Heineke

Dept. of Cardiovascular Research, European Center for Angioscience (ECAS),

Medical Faculty Mannheim, Heidelberg University

Prof. Dr. Carmen Ruiz de Almodóvar

European Center for Angioscience (ECAS)
Institute for Transfusion Medicine/Immunology
Faculty of Medicine Mannheim, Heidelberg University

Lymphatics prevent spreading of cancer cells

Press release German Cancer Research Center (DKFZ), October 26, 2020 

Endothelial cell-specific factor protects metastatic tumor cells

Press release German Cancer Research Center (DKFZ), May 26, 2020 

HIF-1α decelerates natural Killer cells

Press release Medical Faculty Mannheim University Heidelberg May 22, 2020

Prevent metastasis - an antibody with potential

Press release German Cancer Research Center (DKFZ), April 24, 2020 

The role of blood vessels in insulin resistance

Press release German Cancer Research Center (DKFZ), March 27, 2020 

Carmen Ruiz de Almodóvar receives ERC Consolidator Grant

 Press release Medical Faculty Mannheim University Heidelberg Dec. 10, 2019

Andreas Fischer receives Gábor Szász Award

Press release German Cancer Research Center (DKFZ), Oct. 7, 2019

 

Überlebensstrategien im Klub K: Ein bisschen Maß muss sein

Zeitungsartikel der Rhein-Neckar Zeitung vom 13. Juli 2019

for more

 

Blutgefäße spielen bei einer Krebserkrankung eine wichtige Rolle: Sie ermöglichen es den Tumoren, zu wachsen und sich im Körper auszubreiten

Pressemitteilung des Deutschen Krebsforschungszentrums (DKFZ)

 

Bericht im Mannheimer Morgen vom 1. März 2019

Pressemitteilung zum Kickoff Meeting

 

Michael Platten receives the German Cancer Award 2019

Bericht im Mannheimer Morgen vom 2. März 2019

 

Pressemitteilung vom 23.11.2018

Grünes Licht für neuen gefäßbiologischen Sonderforschungsbereich

Die Deutsche Forschungsgemeinschaft (DFG) fördert die Erforschung von Mechanismen, mit denen Blutgefäße die Funktion von Organen während der Entwicklung und bei Krankheitsprozessen steuern, mit mehr als 11 Mio. Euro.

CRC1366

European Center for Angioscience

Medical Faculty Mannheim
Heidelberg University

Ludolf-Krehl-Straße 13-17
D-68167 Mannheim

Phone +49 621/383-71450