2025
Rodriguez Morales D, Larcher V, Ruz Jurado M, Arifaj D, Tombor L, Zanders L, Zeiher AM, Kuppe C, John D, Wagner JUG, Schulz MH, Dimmeler S: Vascular niches are the primary hotspots in cardiac aging. Circ Res. 2025 October 15.
Ruiz de Almodovar C, Dupraz S, Bonanomi D: Neurovascular dynamics in the spinal cord from development to pathophysiology. Neuron. 2025 October 14.
Manickam N, Sultan I, Panthel J, Kujundzic H, Fischer A, Schmitz K, Ruz Jurado M, Rodriguez Morales D, John D, Glaser SF, Stilz KA, Malacarne PF, Brandes RP, Braun T, Lerchenmüller C, Betge F, Abplanalp WT, Alitalo K, Dimmeler S, Wagner JUG: Beneficial effects of vascular endothelial growth factor B gene transfer in the aged heart. Cardiovasc Res. 2025 August 28.
Sieckmann K, Winnerling N, Silva Ribeiro DJ, Yüksel S, Kardinal R, Steinheuer LM, Frechen F, Corrêa LH, Schermann G, Klausen C, Blank-Stein N, Schulte-Schrepping J, Osei-Sarpong C, Becker M, Bonaguro L, Beyer M, May-Simera HL, Zurkovic J, Thiele C, Thurley K, Sorokin L, Ruiz de Almodovar C, Mass E, Wachten D: BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue. EMBO J. 2025 August 20.
Spray L, Richardson G, Haendeler J, Altschmied J, Rumampouw V, Wallis SB, Georgiopoulos G, White S, Unsworth A, Stellos K, Tual-Chalot S, Spyridopoulos I: Cardiovascular inflammaging: Mechanisms, consequences, and therapeutic perspectives. Cell Rep Med. 2025 August 6.
Wardman R, Heineke J: AKT and heart remodelling: too much of a good thing? Eur Heart J. 2025 August 5.
Lan T, Kaminsky S, Wu CC: Ploidy in cardiovascular development and regeneration. Semin Cell Dev Biol. 2025 August.
Wohlfeil SA, Weller C, Dietsch B, Agardy DA, Boschert T, Vormehr SA, Dormann C, Straub N, Häfele V, Platten M, Goerdt S, Géraud C: Neoadjuvant immune checkpoint inhibition improves protection against hepatic melanoma metastasis. Cancer Lett. 2025 July 24.
Mastrangelo A, Robles-Vera I, Mañanes D, Galán M, Femenía-Muiña M, Redondo-Urzainqui A, Barrero-Rodríguez R, Papaioannou E, Amores-Iniesta J, Devesa A, Lobo-González M, Carreras A, Beck KR, Ivarsson S, Gummesson A, Georgiopoulos G, Rodrigo-Tapias M, Martínez-Cano S, Fernández-López I, Nuñez V, Ferrarini A, Inohara N, Stamatelopoulos K, Benguría A, Cibrian D, Sánchez-Madrid F, Alonso-Herranz V, Dopazo A, Barbas C, Vázquez J, López JA, González-Martín A, Nuñez G, Stellos K, Bergström G, Bäckhed F, Fuster V, Ibañez B, Sancho D: Imidazole propionate is a driver and therapeutic target in atherosclerosis. Nature. 2025 July 16.
Hüllwegen M, Kleinert M, von Haehling S, Fischer A: GDF15: from biomarker to target in cancer cachexia. Trends Cancer. 2025 July 9.
Hasan SS, John D, Rudnicki M, AlZaim I, Eberhard D, Moll I, Taylor J, Klein C, von Heesen M, Conradi LC, Adams RH, Lammert E, Kalucka J, Ruhrberg C, Dimmeler S, Fischer A: Obesity drives depot-specific vascular remodeling in male white adipose tissue. Nat Commun. 2025 June 25.
Vlachogiannis NI, Polycarpou-Schwarz M, Avdi AP, Tual-Chalot S, Stellos K: Targeting RNA adenosine editing and modification enzymes for RNA therapeutics. Mol Ther. 2025 June 9.
Winkler M, Staniczek T, Suhayda M, Kürschner-Zacharias SW, Hoffmann J, Cordero J, Kraske L, Maude H, Nagy D, Manco R, Sticht C, Neßling M, Richter K, Dobreva G, Randi AM, Cebola I, Schledzewski K, Reiners-Koch PS, Goerdt S, Schmid CD: Endothelial c-Maf prevents MASLD-like liver fibrosis by regulating chromatin accessibility to suppress pathogenic microvascular cell subsets. JHEP Reports. 2025 June 6.
Liu H, Tang Y, Singh A, Vong J, Cordero J, Mathes A, Gao R, Jia Y, Garvalov BK, Acker T, Poschet G, Hell R, Schneider MA, Heineke J, Wieland T, Barreto G, Cerwenka A, Potente M, Bibli SI, Savai R, Dobreva G: RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α. Nat Commun. 2025 May 28.
Gehrs S, Gu Z, Hey J, Weichenhan D, Buckwalter N, Jakab M, Hotz-Wagenblatt A, Breuer K, Prada ML, Hübschmann D, Schlereth K, Plass C, Augustin H: DNMT3A-dependent DNA methylation shapes the endothelial enhancer landscape. Nucleic Acids Res. 2025 May 22.
Gehrs S, Jakab M, Gutjahr E, Gu Z, Weichenhan D, Mallm JP, Mogler C, Schlesner M, Plass C, Schlereth K, Augustin HG: The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms. Dev Cell. 2025 May 19.
Gupta S, Bajwa GK, El-Sammak H, Mattonet K, Günther S, Looso M, Stainier DYR, Marín-Juez R: The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration. Dev Biol. 2025 May.
Papaioannou S, See JX, Baljkas T, Reiners-Koch P, Winkler M, Cerwenka A, Stojanovic A: Protocol for isolating and purifying murine liver sinusoidal endothelial cells for in vitro culture and functional assays. STAR Protoc. 2025 March 21.
Aubermann F, Seneca S, Hofman T, Garcés-Lázaro I, Ajmail K, Daubner K, Cerwenka A, Platzman I, Spatz JP: Modular droplet-based microfluidic platform for functional phenotypic screening of natural killer cells. Small Methods. 2025 April 21.
Georgiopoulos G, Athanasopoulos S, Mavraganis G, Konstantaki C, Papaioannou M, Delialis D, Angelidakis L, Sachse M, Papoutsis D, Cavlan B, Tual-Chalot S, Zervas G, Sopova K, Mitrakou A, Stellos K, Stamatelopoulos K: Incremental value of blood-based markers of liver fibrosis in cardiovascular risk stratification. J Clin Endocrinol Metab. 2025 March 17.
Mavraganis G, Georgiopoulos G, Zervas G, Aivalioti E, Delialis D, Petropoulos I, Rachiotis N, Konstantaki C, Moustou C, Dimopoulou MA, Sachse M, Tual-Chalot S, Sopova K, Psimmenou E, Stellos K, Stamatelopoulos K: Circulating amyloid beta 1-40 peptide as an associate of renal function decline. Eur J Clin Invest. 2025 February 24.
Liberale L, Tual-Chalot S, Sedej S, Ministrini S, Georgiopoulos G, Grunewald M, Bäck M, Bochaton-Piallat ML, Boon RA, Ramos GC, de Winther MPJ, Drosatos K, Evans PC, Ferguson JF, Forslund-Startceva SK, Goettsch C, Giacca M, Haendeler J, Kallikourdis M, Ketelhuth DFJ, Koenen RR, Lacolley P, Lutgens E, Maffia P, Miwa S, Monaco C, Montecucco F, Norata GD, Osto E, Richardson GD, Riksen NP, Soehnlein O, Spyridopoulos I, Van Linthout S, Vilahur G, Wentzel JJ, Andrés V, Badimon L, Benetos A, Binder CJ, Brandes RP, Crea F, Furman D, Gorbunova V, Guzik TJ, Hill JA, Lüscher TF, Mittelbrunn M, Nencioni A, Netea MG, Passos JF, Stamatelopoulos KS, Tavernarakis N, Ungvari Z, Wu JC, Kirkland JL, Camici GG, Dimmeler S, Kroemer G, Abdellatif M, Stellos K: Roadmap for alleviating the manifestations of ageing in the cardiovascular system. Nat Rev Cardiol. 2025 February 19.
Petrovic D, Slade L, Paikopoulos Y, D'Andrea D, Savic N, Stancic A, Miljkovic JL, Vignane T, Drekolia MK, Mladenovic D, Sutulovic N, Refeyton A, Kolakovic M, Jovanovic VM, Zivanovic J, Miler M, Vellecco V, Brancaleone V, Bucci M, Casey AM, Yu C, Kasarla SS, Smith KW, Kalfe-Yildiz A, Stenzel M, Miranda-Vizuete A, Hergenröder R, Phapale P, Stanojlovic O, Ivanovic-Burmazovic I, Vlaski-Lafarge M, Bibli SI, Murphy MP, Otasevic V, Filipovic MR: Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation. Cell Metab. 2025 February 4.
Fan X, Yang G, Wang Y, Shi H, Nitschke K, Sattler K, Abumayyaleh M, Cyganek L, Nuhn P, Worst T, Liao B, Dobreva G, Duerschmied D, Zhou X, El-Battrawy I, Akin I: Exosomal mir-126-3p derived from endothelial cells induces ion channel dysfunction by targeting RGS3 signaling in cardiomyocytes: a novel mechanism in Takotsubo cardiomyopathy. Stem Cell Res Ther. 2025 February 4.
Hoffmann J, Schüler J, Dietsch B, Kürschner-Zacharias SW, Sticht C, Trogisch FA, Schreitmüller M, Baljkas T, Schledzewski K, Reinhart M, Wohlfeil SA, Winkler M, Schmid CD, Heineke J, Géraud C, Goerdt S, Reiners-Koch PS, Olsavszky V: Steatohepatitis-induced vascular niche alterations promote melanoma metastasis. Cancer Metab. 2025 January 28.
Aivalioti E, Georgiopoulos G, Tual-Chalot S, Bampatsias D, Delialis D, Sopova K, Drakos SG, Stellos K, Stamatelopoulos K: Amyloid-beta metabolism in age-related neurocardiovascular diseases. Eur Heart J. 2025 January 16.
Babin-Ebell Gonçalves A, Mao Y, Baljkas T, Wiedmann F, Eis L, Pilz F, Winkler M, Kürschner-Zacharias SW, Hoffarth M, Funaya C, Shahidi R, Géraud C, Wu CC, Schmidt C, Goerdt S, Reiners-Koch PS, Singhal M: A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells. Commun Biol. 2025 January 8.
2024
Kunze R, Wacker P, Breuer P, Nasyrov E, Kur IM, Weigert A, Wagner AH, Marti HH, Korff T: Adequate post-ischemic reperfusion of the mouse brain requires endothelial NFAT5. Acta Neuropathol Commun. 2024 December 22.
Koh BI, Mohanakrishnan V, Jeong HW, Park H, Kruse K, Choi YJ, Nieminen-Kelhä M, Kumar R, Pereira RS, Adams S, Lee HJ, Bixel MG, Vajkoczy P, Krause DS, Adams RH: Adult skull bone marrow is an expanding and resilient haematopoietic reservoir. Nature. 2024 November 13.
Nording H, Baron L, Sauter M, Lübken A, Rawish E, Szepanowski R, von Esebeck J, Sun Y, Emami H, Meusel M, Saraei R, Schanze N, Gorantla SP, von Bubnoff N, Geisler T, von Hundelshausen P, Stellos K, Marquardt J, Sadik CD, Köhl J, Duerschmied D, Kleinschnitz C, Langer HF: Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor-modulating factors. Blood Adv. 2023 November 14. Erratum in: Blood Adv. 2024 November 12.
Mohanakrishnan V, Sivaraj KK, Jeong HW, Bovay E, Dharmalingam B, Bixel MG, Dinh VV, Petkova M, Paredes Ugarte I, Kuo YT, Gurusamy M, Raftrey B, Chu NTL, Das S, Rios Coronado PE, Stehling M, Sävendahl L, Chagin AS, Mäkinen T, Red-Horse K, Adams RH: Specialized post-arterial capillaries facilitate adult bone remodelling. Nat Cell Biol. 2024 November 11.
Laban H, Siegmund S, Schlereth K, Trogisch FA, Ablieh A, Brandenburg L, Weigert A, De La Torre C, Mogler C, Hecker M, Kuebler WM, Korff T: Nuclear factor of activated T-cells 5 is indispensable for a balanced adaptive transcriptional response of lung endothelial cells to hypoxia. Cardiovasc Res. 2024 November 5.
Tetik-Elsherbiny N, Elsherbiny A, Setya A, Gahn J, Tang Y, Gupta P, Dou Y, Serke H, Wieland T, Dubrac A, Heineke J, Potente M, Cordero J, Ola R, Dobreva G: RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth. Nat Cardiovasc Res. 2024 September 25.
Özbay Kurt FG, Cicortas BA, Balzasch BM, De la Torre C, Ast V, Tavukcuoglu E, Ak C, Wohlfeil SA, Cerwenka A, Utikal J, Umansky V: S100A9 and HMGB1 orchestrate MDSC-mediated immunosuppression in melanoma through TLR4 signaling. J Immunother Cancer. 2024 September 11.
Augustin HG, Koh GY: A systems view of the vascular endothelium in health and disease. Cell. 2024 September 5.
Keles M, Grein S, Froese N, Wirth D, Trogisch FA, Wardman R, Hemanna S, Weinzierl N, Koch PS, Uhlig S, Lomada S, Dittrich GM, Szaroszyk M, Haustein R, Hegermann J, Martin-Garrido A, Bauersachs J, Frank D, Frey N, Bieback K, Cordero J, Dobreva G, Wieland T, Heineke J: Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling. Mol Ther Nucleic Acids. 2024 August 15.
Cano E, Schwarzkopf J, Kanda M, Lindberg EL, Hollfinger I, Pogontke C, Braeuning C, Fischer C, Hübner N, Gerhardt H: Intramyocardial sprouting tip cells specify coronary arterialization. Circ Res. 2024 August 2.
Sivaraj KK, Majev PG, Dharmalingam B, Schröder S, Banjanin B, Stehling M, Zeuschner D, Nordheim A, Schneider RK, Adams RH: Endothelial LATS2 is a suppressor of bone marrow fibrosis. Nat Cardiovasc Res. 2024 July 29.
Park H, Song J, Jeong HW, Grönloh MLB, Koh BI, Bovay E, Kim KP, Klotz L, Thistlethwaite PA, van Buul JD, Sorokin L, Adams RH: Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis. Nat Commun. 2024 July 25.
Hofman T, Ng SW, Garcés-Lázaro I, Heigwer F, Boutros M, Cerwenka A: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets. J Immunother Cancer. 2024 July 1.
Delialis D, Georgiopoulos G, Tual-Chalot S, Angelidakis L, Aivalioti E, Mavraganis G, Sopova K, Argyris A, Kostakou P, Konstantaki C, Papaioannou M, Tsilimigras D, Chatoupis K, Zacharoulis AA, Galyfos G, Sigala F, Stellos K & Stamatelopoulos K: Amyloid beta is associated with carotid wall echolucency and atherosclerotic plaque composition. Sci Rep. 2024 June 28.
Lindner S, Hoermann C, Teichert J, Ziyadova S, Michels-Zetsche JD, Neetz B, Herth FJF, Duerschmied D, Britsch S: Correlation of diaphragm thickening fraction and oesophageal pressure swing in non-invasive ventilation of healthy subjects. BMC Pulm Med. 2024 June 21.
Hobohm L, Farmakis IT, Duerschmied D, Keller K: The current evidence of pulmonary embolism response teams and their role in future. Hamostaseologie. 2024 June.
Cordero J, Elsherbiny A, Wang Y, Jürgensen L, Constanty F, Günther S, Boerries M, Heineke J, Beisaw A, Leuschner F, Hassel D, Dobreva G: Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration. Nucleic Acids Res. 2024 May 8.
Kilian M, Friedrich MJ, Lu KH, Vonhören D, Jansky S, Michel J, Keib A, Stange S, Hackert N, Kehl N, Hahn M, Habel A, Jung S, Jähne K, Sahm F, Betge J, Cerwenka A, Westermann F, Dreger P, Raab MS, Meindl-Beinker NM, Ebert M, Bunse L, Müller-Tidow C, Schmitt M, Platten M: The immunoglobulin superfamily ligand B7H6 subjects T cell responses to NK cell surveillance. Sci Immunol. 2024 May 3.
Jakab M, Lee KH, Uvarovskii A, Ovchinnikova S, Kulkarni SR, Jakab S, Rostalski T, Spegg C, Anders S, Augustin HG: Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency. Nat Cancer. 2024 May.
Jeong M, Cortopassi F, See JX, De La Torre C, Cerwenka A, Stojanovic A: Vitamin A-treated natural killer cells reduce interferon-gamma production and support regulatory T-cell differentiation. Eur J Immunol. 2024 April 9.
Trogisch FA, Abouissa A, Keles M, Birke A, Fuhrmann M, Dittrich GM, Weinzierl N, Wink E, Cordero J, Elsherbiny A, Martin-Garrido A, Grein S, Hemanna S, Hofmann E, Nicin L, Bibli SI, Airik R, Kispert A, Kist R, Quanchao S, Kürschner SW, Winkler M, Gretz N, Mogler C, Korff T, Koch PS, Dimmeler S, Dobreva G, Heineke J: Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9. Sci Transl Med. 2024 February 28.
Jakab M, Lee KH, Uvarovskii A, Ovchinnikova S, Kulkarni SR, Jakab S, Rostalski T, Spegg C, Anders S, Augustin HG: Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency. Nat Cancer. 2024 February 2.
Fischer A, Alsina-Sanchis E: Disturbed endothelial cell signaling in tumor progression and therapy resistance. Curr Opin Cell Biol. 2024 February.
Drekolia MK, Karantanou C, Wittig I, Li Y, Fuhrmann DC, Brüne B, Katsouda A, Hu J, Papapetropoulos A, Bibli SI: Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging. Redox Biol. 2024 February.
Wohlfeil SA, Olsavszky A, Irkens AL, Häfele V, Dietsch B, Straub N, Goerdt S, Géraud C: Deficiency of stabilin-1 in the context of hepatic melanoma metastasis. Cancers (Basel). 2024 January 19.
Lindner S, Teichert J, Hoermann C, Michels JD, Herth FJF, Duerschmied D, Britsch S: Mask continuous positive airway pressure increases diaphragm thickening fraction in healthy subjects. Respiration. 2024 January 16.
2023
Langer HF: An unexpected cellular fountain of youth: platelets provide factors rejuvenating brain functions. Signal Transduct Target Ther. 2023 December 29.
Sahm K, Kessler T, Eisele P, Ratliff M, Sperk E, König L, Breckwoldt MO, Seliger C, Mildenberger I, Schrimpf D, Herold-Mende C, Zeiner PS, Tabatabai G, Meuth SG, Capper D, Bendszus M, von Deimling A, Wick W, Sahm F, Platten M: Concurrent gliomas in patients with multiple sclerosis. Commun Med (Lond). 2023 December 18.
Lin Y, Gahn J, Banerjee K, Dobreva G, Singhal M, Dubrac A, Ola R: Role of endothelial PDGFB in arterio-venous malformations pathogenesis. Angiogenesis. 2023 December 09.
Groth C, Maric J, Garcés Lázaro I, Hofman T, Zhang Z, Ni Y, Keller F, Seufert I, Hofmann M, Neumann-Haefelin C, Sticht C, Rippe K, Urban S, Cerwenka A: Hepatitis D infection induces IFN-β-mediated NK cell activation and TRAIL-dependent cytotoxicity. Front Immunol. 2023 December 8.
Nording H, Baron L, Sauter M, Lübken A, Rawish E, Szepanowski R, von Esebeck J, Sun Y, Emami H, Meusel M, Saraei R, Schanze N, Gorantla SP, von Bubnoff N, Geisler T, von Hundelshausen P, Stellos K, Marquardt J, Sadik CD, Köhl J, Duerschmied D, Kleinschnitz C, Langer HF: Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor-modulating factors. Blood Adv. 2023 November 14.
Rodríguez-Montes L, Ovchinnikova S, Yuan X, Studer T, Sarropoulos I, Anders S, Kaessmann H, Cardoso-Moreira M: Sex-biased gene expression across mammalian organ development and evolution. Science. 2023 November 3.
Hu J, Leisegang MS, Looso M, Drekolia MK, Wittig J, Mettner J, Karantanou C, Kyselova A, Dumbovic G, Li X, Li Y, Guenther S, John D, Siragusa M, Zukunft S, Oo JA, Wittig I, Hille S, Weigert A, Knapp S, Brandes RP, Müller OJ, Papapetropoulos A, Sigala F, Dobreva G, Kojonazarov B, Fleming I, Bibli SI: Disrupted binding of Cystathionine γ-lyase to p53 promotes endothelial senescence. Circ Res. 2023 October 27.
Nording H, Baron L, Lübken A, Emami H, von Esebeck J, Meusel M, Sadik C, Schanze N, Duerschmied D, Köhl J, Münch G, Langer HF: The platelet anaphylatoxin receptor C5aR1 (CD88) is a promising target for modulating vessel growth in response to ischemia a. TH Open. 2023 October 19.
Grassl N, Sahm K, Süße H, Poschke I, Bunse L, Bunse T, Boschert T, Mildenberger I, Rupp AK, Ewinger MP, Lanz LM, Denk M, Tabatabai G, Ronellenfitsch MW, Herrlinger U, Glas M, Krex D, Vajkoczy P, Wick A, Harting I, Sahm F, von Deimling A, Bendszus M, Wick W, Platten M: INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas. Neurol Res Pract. 2023 October 19.
De Angelis Rigotti F, Wiedmann L, Hubert MO, Vacca M, Hasan SS, Moll I, Carvajal S, Jiménez W, Starostecka M, Billeter AT, Müller-Stich B, Wolff G, Ekim-Üstünel B, Herzig S, Fandos-Ramo C, Krätzner R, Reich M, Keitel-Anselmino V, Heikenwälder M, Mogler C, Fischer A, Rodriguez-Vita J: Semaphorin 3C exacerbates liver fibrosis. Hepatology. 2023 October 1.
Georgiopoulos G, Kraler S, Mueller-Hennessen M, Delialis D, Mavraganis G, Sopova K, Wenzl FA, Räber L, Biener M, Stähli BE, Maneta E, Spray L, Iglesias JF, Coelho-Lima J, Tual-Chalot S, Muller O, Mach F, Frey N, Duerschmied D, Langer HF, Katus H, Roffi M, Camici GG, Mueller C, Giannitsis E, Spyridopoulos I, Lüscher TF, Stellos K, Stamatelopoulos K: Modification of the GRACE risk score for risk prediction in patients with acute coronary syndromes. JAMA Cardiol. 2023 October 1.
Wardman R, Keles M, Pachkiv I, Hemanna S, Grein S, Schwarz J, Stein F, Ola R, Dobreva G, Hentze MW, Heineke J: RNA-binding proteins regulate post-transcriptional responses to TGF-β to coordinate function and mesenchymal activation of murine endothelial cells. Arterioscler Thromb Vasc Biol. 2023 October 1.
Taylor J, Uhl L, Moll I, Hasan SS, Wiedmann L, Morgenstern J, Giaimo BD, Friedrich T, Alsina-Sanchis E, De Angelis Rigotti F, Mülfarth R, Kaltenbach S, Schenk D, Nickel F, Fleming T, Sprinzak D, Mogler C, Korff T, Billeter AT, Müller-Stich BP, Berriel Diaz M, Borggrefe T, Herzig S, Rohm M, Rodriguez-Vita J, Fischer A: Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia. Nat Cancer. 2023 September 25.
Hunger J, Schregel K, Boztepe B, Agardy DA, Turco V, Karimian-Jazi K, Weidenfeld I, Streibel Y, Fischer M, Sturm V, Santarella-Mellwig R, Kilian M, Jähne K, Sahm K, Wick W, Bunse L, Heiland S, Bunse T, Bendszus M, Platten M, Breckwoldt MO: In vivo nanoparticle-based T cell imaging can predict therapy response towards adoptive T cell therapy in experimental glioma. Theranostics. 2023 September 25.
Grassl N, Poschke I, Lindner K, Bunse L, Mildenberger I, Boschert T, Jähne K, Green EW, Hülsmeyer I, Jünger S, Kessler T, Suwala AK, Eisele P, Breckwoldt MO, Vajkoczy P, Grauer OM, Herrlinger U, Tonn JC, Denk M, Sahm F, Bendszus M, von Deimling A, Winkler F, Wick W, Platten M, Sahm K: A H3K27M-targeted vaccine in adults with diffuse midline glioma. Nat Med. 2023 September 21.
Banerjee K, Lin Y, Gahn J, Cordero J, Gupta P, Mohamed I, Graupera M, Dobreva G, Schwartz MA, Ola R: SMAD4 maintains the fluid shear stress set point to protect against arterial-venous malformations. J Clin Invest. 2023 September 15.
Velichkova G, Dobreva G: Human pluripotent stem cell-based models of heart development and disease. Cells Dev. 2023 September.
Krzistetzko J, Géraud C, Dormann C, Riedel A, Leibing T: Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice. FEBS Open Bio. 2024 September.
Wardman R, Keles M, Pachkiv I, Hemanna S, Grein S, Schwarz J, Stein F, Ola R, Dobreva G, Hentze MW, Heineke J: RNA-binding proteins regulate post-transcriptional responses to TGF-β to coordinate function and mesenchymal activation of murine endothelial cells. Arterioscler Thromb Vasc Biol. 2023 August 31.
Papaioannou S, See JX, Jeong M, De La Torre C, Ast V, Reiners-Koch PS, Sati A, Mogler C, Platten M, Cerwenka A, Stojanovic A: Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury. Cell Rep. 2023 August 29.
Wagner JUG, Tombor LS, Malacarne PF, Kettenhausen LM, Panthel J, Kujundzic H, Manickam N, Schmitz K, Cipca M, Stilz KA, Fischer A, Muhly-Reinholz M, Abplanalp WT, John D, Mohanta SK, Weber C, Habenicht AJR, Buchmann GK, Angendohr S, Amin E, Scherschel K, Klöcker N, Kelm M, Schüttler D, Clauss S, Günther S, Boettger T, Braun T, Bär C, Pham MD, Krishnan J, Hille S, Müller OJ, Bozoglu T, Kupatt C, Nardini E, Osmanagic-Myers S, Meyer C, Zeiher AM, Brandes RP, Luxán G, Dimmeler S: Aging impairs the neurovascular interface in the heart. Science. 2023 August 25.
Lee C, Chen R, Sun G, Liu X, Lin X, He C, Xing L, Liu L, Jensen LD, Kumar A, Langer HF, Ren X, Zhang J, Huang L, Yin X, Kim J, Zhu J, Huang G, Li J, Lu W, Chen W, Liu J, Hu J, Sun Q, Lu W, Fang L, Wang S, Kuang H, Zhang Y, Tian G, Mi J, Kang BA, Narazaki M, Prodeus A, Schoonjans L, Ornitz DM, Gariepy J, Eelen G, Dewerchin M, Yang Y, Ou JS, Mora A, Yao J, Zhao C, Liu Y, Carmeliet P, Cao Y, Li X: VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway. Signal Transduct Target Ther. 2023 August 18.
Papaioannou S, See JX, Jeong M, De La Torre C, Ast V, Reiners-Koch PS, Sati A, Mogler C, Platten M, Cerwenka A, Stojanovic A: Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury. Cell Rep. 2023 July 19.
Krzistetzko J, Géraud C, Dormann C, Riedel A, Leibing T: Association of differentially altered liver fibrosis with deposition of TGFBi in stabilin-deficient mice. Int J Mol Sci. 2023 June 30.
Leibing T, Riedel A, Xi Y, Adrian M, Krzistetzko J, Kirkamm C, Dormann C, Schledzewski K, Goerdt S, Géraud C: Deficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice. Aging Cell. 2023 June 25.
Sopova K, Tual-Chalot S, Mueller-Hennessen M, Vlachogiannis NI, Georgiopoulos G, Biener M, Sachse M, Turchinovich A, Polycarpou-Schwarz M, Spray L, Maneta E, Bennaceur K, Mohammad A, Richardson GD, Gatsiou A, Langer HF, Frey N, Stamatelopoulos K, Heineke J, Duerschmied D, Giannitsis E, Spyridopoulos I, Stellos K: Effector T cell chemokine IP-10 predicts cardiac recovery and clinical outcomes post-myocardial infarction. Front Immunol. 2023 June 22.
Sachse M, Tual-Chalot S, Ciliberti G, Amponsah-Offeh M, Stamatelopoulos K, Gatsiou A, Stellos K: RNA-binding proteins in vascular inflammation and atherosclerosis. Atherosclerosis. 2023 June.
Balzasch BM, Cerwenka A: Microenvironmental signals shaping NK-cell reactivity in cancer. Eur J Immunol. 2023 May 17.
Dietsch B, Weller C, Sticht C, de la Torre C, Kramer M, Goerdt S, Géraud C, Wohlfeil SA: Hepatic passaging of NRAS-mutant melanoma influences adhesive properties and metastatic pattern. BMC Cancer. 2023 May 13.
Gatsiou A, Tual-Chalot S, Napoli M, Ortega-Gomez A, Regen T, Badolia R, Cesarini V, Garcia-Gonzalez C, Chevre R, Ciliberti G, Silvestre-Roig C, Martini M, Hoffmann J, Hamouche R, Visker JR, Diakos N, Wietelmann A, Silvestris DA, Georgiopoulos G, Moshfegh A, Schneider A, Chen W, Guenther S, Backs J, Kwak S, Selzman CH, Stamatelopoulos K, Rose-John S, Trautwein C, Spyridopoulos I, Braun T, Waisman A, Gallo A, Drakos SG, Dimmeler S, Sperandio M, Soehnlein O, Stellos K: The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Immunity. 2023 May 9.
Wiedmann L, De Angelis Rigotti F, Vaquero-Siguero N, Donato E, Espinet E, Moll I, Alsina-Sanchis E, Bohnenberger H, Fernandez-Florido E, Mülfarth R, Vacca M, Gerwing J, Conradi LC, Ströbel P, Trumpp A, Mogler C, Fischer A, Rodriguez-Vita J: HAPLN1 potentiates peritoneal metastasis in pancreatic cancer. Nat Commun. 2023 April 24.
Drexler S, Cai C, Hartmann AL, Moch D, Gaitantzi H, Ney T, Kraemer M, Chu Y, Zheng Y, Rahbari M, Treffs A, Reiser A, Lenoir B, Valous NA, Jäger D, Birgin E, Sawant TA, Li Q, Xu K, Dong L, Otto M, Itzel T, Teufel A, Gretz N, Hawinkels LJAC, Sánchez A, Herrera B, Schubert R, Moshage H, Reissfelder C, Ebert MPA, Rahbari NN, Breitkopf-Heinlein K: Intestinal BMP-9 locally upregulates FGF19 and is down-regulated in obese patients with diabetes. Mol Cell Endocrinol. 2023 April 19.
De Angelis Rigotti F, Wiedmann L, Hubert MO, Vacca M, Hasan SS, Moll I, Carvajal S, Jiménez W, Starostecka M, Billeter AT, Müller-Stich B, Wolff G, Ekim-Üstünel B, Herzig S, Fandos-Ramo C, Krätzner R, Reich M, Keitel-Anselmino V, Heikenwälder M, Mogler C, Fischer A, Rodriguez-Vita J: Semaphorin 3C exacerbates liver fibrosis. Hepatology. 2023 April 15.
Maneta E, Aivalioti E, Tual-Chalot S, Emini Veseli B, Gatsiou A, Stamatelopoulos K, Stellos K: Endothelial dysfunction and immunothrombosis in sepsis. Front Immunol. 2023 April 4.
Schmid CD, Olsavszky V, Reinhart M, Weyer V, Trogisch FA, Sticht C, Winkler M, Kürschner SW, Hoffmann J, Ola R, Staniczek T, Heineke J, Straub BK, Mittler J, Schledzewski K, Ten Dijke P, Richter K, Dooley S, Géraud C, Goerdt S, Koch PS: ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver. Hepatology. 2023 April 1.
Hasan SS, Fischer A: Notch signaling in the vasculature: Angiogenesis and angiocrine functions. Cold Spring Harb Perspect Med. 2023 February 1.
Wittig J, Drekolia MK, Kyselova A, Delgado Lagos F, Bochenek ML, Hu J, Schäfer K, Fleming I, Bibli SI: Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation. Redox Biol. 2023 April 3.
Huseynov A, Reinhardt J, Chandra L, Dürschmied D, Langer HF: Novel aspects targeting platelets in atherosclerotic cardiovascular disease-A translational perspective. Int J Mol Sci. 2023 March 27.
Sauter R, Lin C, Magunia H, Schreieck J, Dürschmied D, Gawaz M, Patzelt J, Langer HF: Improved mid-term stability of MR reduction with an increased number of clips after percutaneous mitral valve repair in functional MR. Int J Cardiol Heart Vasc. 2023 March 10.
Kilian M, Sheinin R, Tan CL, Friedrich M, Krämer C, Kaminitz A, Sanghvi K, Lindner K, Chih YC, Cichon F, Richter B, Jung S, Jähne K, Ratliff M, Prins RM, Etminan N, von Deimling A, Wick W, Madi A, Bunse L, Platten M: MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors. Cancer Cell. 2023 February 13.
Turco V, Pfleiderer K, Hunger J, Horvat NK, Karimian-Jazi K, Schregel K, Fischer M, Brugnara G, Jähne K, Sturm V, Streibel Y, Nguyen D, Altamura S, Agardy DA, Soni SS, Alsasa A, Bunse T, Schlesner M, Muckenthaler MU, Weissleder R, Wick W, Heiland S, Vollmuth P, Bendszus M, Rodell CB, Breckwoldt MO, Platten M: T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles. Nat Commun. 2023 February 11.
Abu Hejleh AP, Huck K, Jähne K, Tan CL, Lanz TV, Epping L, Sonner JK, Meuth SG, Henneberg A, Opitz CA, Herold-Mende C, Sahm F, Platten M, Sahm K: Endothelial indoleamine-2,3-dioxygenase-1 is not critically involved in regulating antitumor immunity in the central nervous system. Int J Tryptophan Res. 2023 February 9.
Hübers C, Abdul Pari AA, Grieshober D, Petkov M, Schmidt A, Messmer T, Heyer CM, Schölch S, Kapel SS, Gengenbacher N, Singhal M, Schieb B, Fricke C, Will R, Remans K, Utikal JS, Reissfelder C, Schlesner M, Hodivala-Dilke KM, Kersten S, Goerdt S, Augustin HG, Felcht M: Primary tumor-derived systemic nANGPTL4 inhibits metastasis. J Exp Med. 2023 January 2.
Haustein R, Trogisch FA, Keles M, Hille S, Fuhrmann M, Weinzierl N, Hemanna S, Thackeray J, Dou Y, Zwadlo C, Froese N, Cordero J, Bengel F, Müller OJ, Bauersachs J, Dobreva G, Heineke J: C1q and tumor necrosis factor related protein 9 protects from diabetic cardiomyopathy by alleviating cardiac onsulin resistance and inflammation. Cells. 2023 January 29.
2022
Vieira JR, Shah B, Dupraz S, Paredes I, Himmels P, Schermann G, Adler H, Motta A, Gärtner L, Navarro-Aragall A, Ioannou E, Dyukova E, Bonnavion R, Fischer A, Bonanomi D, Bradke F, Ruhrberg C, Ruiz de Almodóvar C: Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development. Neuron. 2022 December 21.
Alsina-Sanchis E*, Mülfarth R*, Moll I, Böhn S, Wiedmann L, Jordana-Urriza L, Ziegelbauer T, Zimmer E, Taylor J, De Angelis Rigotti F, Stögbauer A, Giaimo BD, Cerwenka A, Borggrefe T, Fischer A*, Rodriguez-Vita J*: Endothelial Rbpj is essential for the education of tumour-associated macrophages. Cancer Res. 2022 December 2.
Wang Y, Elsherbiny A, Kessler L, Cordero J, Shi H, Serke H, Lityagina O, Trogisch FA, Mohammadi MM, El-Battrawy I, Backs J, Wieland T, Heineke J, Dobreva G: Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function. Nat Commun. 2022 November 4.
Manta CP, Leibing T, Friedrich M, Nolte H, Adrian M, Schledzewski K, Krzistetzko J, Kirkamm C, David Schmid C, Xi Y, Stojanovic A, Tonack S, de la Torre C, Hammad S, Offermanns S, Krüger M, Cerwenka A, Platten M, Goerdt S, Géraud C: Targeting of scavenger receptors Stabilin-1 and Stabilin-2 ameliorates atherosclerosis by a plasma proteome switch mediating monocyte/macrophage suppression. Circulation. 2022, November 3.
Drekolia MK, Talyan S, Emídio RC, Boon RA, Guenther S, Looso M, Dumbović G and Bibli SI: Unravelling the impact of aging on the human endothelial lncRNA transcriptome. Front. Genet. 2022, October 21.
Hübers C, Abdul Pari AA, Grieshober D, Petkov M, Schmidt A, Messmer T, Heyer CM, Schölch S, Kapel SS, Gengenbacher N, Singhal M, Schieb B, Fricke C, Will R, Remans K, Utikal JS, Reissfelder C, Schlesner M, Hodivala-Dilke KM, Kersten S, Goerdt S, Augustin HG, Felcht M: Primary tumor-derived systemic nANGPTL4 inhibits metastasis. J Exp Med. [Epub] 2022, October 21
Kessler L, Gao R, Tetik-Elsherbiny N, Lityagina O, Zhailauova A, Ren Y, Trogisch FA, Cordero J, Dou Y, Wang Y, Chichelnitskiy E, Kraske JA, Schäfer PL, Wu CC, Barreto G, Potente M, Wieland T, Ola R, Heineke J, Dobreva G: Rnf20 shapes the endothelial control of heart morphogenesis and function. BioRxiv. 2022, September 17.
Hu J, Leisegang MS, Looso M, Dumbovic G, Wittig J, Drekolia MK, Guenther S, John D, Siragusa M, Zukunft S, Oo J, Wittig W, Hille S, Weigert A, Knapp S, Brandes RP, Mueller OJ, Papapetropoulos A, Sigala F, Dobreva G, Fleming I, Bibli SI: A novel role for cystathionine gamma lyase in the control of p53: impact on endothelial senescence and metabolic reprograming. BioRxiv. 2022, September 5.
Cheng S, Mittnenzweig M, Mayshar Y, Lifshitz A, Dunjic M, Rais Y, Ben-Yair R, Gehrs S, Chomsky E, Mukamel Z, Schlereth K, Reines N, Orenbuch AH, Tanay A, Stelzer Y: The intrinsic and extrinsic effects of Tet proteins during gastrulation. Cell. 2022, August 18.
Gehrs S, Jakab M, Gutjahr E, Gu Z, Weichenhan D, Mogler C, Schlesner M, Plass C, Augustin HG, Schlereth K: Endothelial Dnmt3a controls placenta vascularization and function to support fetal growth. BioRxiv. 2022, July 29.
Papaioannou S, See J-X, Jeong M, De La Torre C, Reiners-Koch PS, Batra A, Mogler C, Platten M, Cerwenka A, Stojanovic A: Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury. BioRxiv. 2022, July 16.
Tulessin M, Sarker RSJ, Griger J, Leibing T, Géraud C, Weichert W, Steiger K, Mogler C: Vascular remodeling is a crucial event in the early phase of hepatocarcinogenesis in rodent models for liver tumorigenesis. Cells. 2022, July 6.
Banerjee K, Gahn J, Lin Y, Lei X, Gupta P, Graupera M, Schwartz MA, Ola R: Shear stress induced KLF4 is a key determinant in AVM pathogenesis. BioRxiv. 2022, July 4.
Sahm K, Kessler T, Eisele P, Ratliff M, Sperk E, Koenig L, Breckwoldt M, Seliger C, Mildenberger I, Schrimpf D, Herold-Mende C, Zeiner P, Tabatabai G, Meuth S, Capper D, Bendszus M, von Deimling A, Wick W, Sahm F, Platten M: Concurrent gliomas in patients with multiple sclerosis. MedRxiv. 2022, July 4.
Schmid CD, Olsavszky V, Reinhart M, Weyer V, Trogisch FA, Sticht C, Winkler M, Kürschner SW, Hoffmann J, Ola R, Staniczek T, Heineke J, Straub BK, Mittler J, Schledzewski K, ten Dijke P, Dooley S, Géraud C, Goerdt S, Koch PS: ALK1 controls hepatic vessel formation, angiodiversity, and angio-crine functions in hereditary hemorrhagic telangiectasia of the liver. Hepatology. 2022, July 1.
Manta CP, Leibing T, Friedrich M, Nolte H, Adrian M, Schledzewski K, Krzistetzko J, Kirkamm C, Schmid CD, Xi Y, Stojanovic A, Tonack S, de la Torre C, Hammad S, Offermanns S, Krüger M, Cerwenka A, Platten M, Goerdt S#, Géraud C#: Targeting of scavenger receptors Stabilin-1 and Stabilin-2 ameliorates atherosclerosis by a plasma proteome switch mediating monocyte/macrophage suppression. BioRxiv. 2022, July 1.
Jeong HW, Dieguez-Hurtado R, Arf H, Song J, Park H, Kruse K, Sorokin L, Adams RH: Single cell transcriptomics reveals functionally specialized vascular endothelium in brain. BioRxiv. 2022, June 13.
Garcés-Lázaro I, Kotzur R, Cerwenka A, Mandelboim O: NK cells under hypoxia: The two faces of vascularization in tumor and pregnancy. Front Immunol. 2022, June 13.
Kilian M, Sheinin R, Tan CL, Krämer C, Friedrich M, Kaminitz A, Sanghvi K, Lindner K, Cichon F, Jung S, Jähne K, Ratliff M, Prins R, von Deimling A, Wick W, Madi A, Bunse L, Platten M: MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors. BioRxiv. 2022, June 12.
Tisch N, Mogler C, Stojanovic A, Luck R, Korhonen EA, Ellerkmann A, Adler H, Schermann G, Erkert L, Patankar JV, Karakatsani A, Scherr AL, Fuchs Y, Cerwenka A, Wirtz S, Köhler BC, Augustin HG, Becker C, Schmidt T, Ruiz de Almodovar C: Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice. EMBO Mol Med. 2022, June 8.
S Ovchinnikova, S Anders: R/LinkedCharts: A novel approach for simple but powerful interactive data analysis. BioRxiv. 2022, June 1.
Friedrich M, Hahn M, Michel J, Sankowski R, Kilian M, Kehl N, Günter M, Bunse T, Pusch S, von Deimling A, Wick W, Autenrieth SE, Prinz M, Platten M, Bunse L: Dysfunctional dendritic cells limit antigen-specific T cell response in glioma. Neuro-Oncol. 2022, May 24.
Jakab M, Rostalski T, Lee KH, Mogler C, Augustin HG: Tie2 receptor in tumor-infiltrating macrophages is dispensable for tumor angiogenesis and tumor relapse after chemotherapy. Cancer Res. 2022, April 1.
El-Sammak H, Yang B, Guenther S, Chen W, Marín-Juez R, Stainier DYR: A Vegfc-Emilin2a-Cxcl8a signaling axis required for zebrafish cardiac regeneration. Circ Res. 2022, March 10.
Coxam B, Collins RT, Hussmann M, Huisman Y, Meier K, Jung S, Bartels-Klein E, Szymborska A, Finotto A, Helker CSM, Stainier DYR, Schulte-Merker S, Gerhardt H: Svep1 stabilises developmental vascular anastomosis in reduced flow conditions. Development. 2022, March 15.
Liu Y, Chen Q, Jeong HW, Koh BI, Watson EC, Xu C, Stehling M, Zhou B, Adams RH: A specialized bone marrow microenvironment for fetal haematopoiesis. Nat Commun. 2022, March 14.
Siegler J-J, Correia MP, Hofman T, Prager I, Birgin E, Rahbari NN, Watzl C, Stojanovic A*, Cerwenka A*: Human ILC3 exert TRAIL-mediated cytotoxicity towards cancer cells. Front Immunol. 2022, March 1.
Froese N, Cordero J, Abouissa A, Trogisch FA, Grein S, Szaroszyk M, Wang Y, Gigina A, Korf-Klingebiel M, Bosnjak B, Davenport CF, Wiehlmann, L, Geffers R, Riechert E, Jürgensen L, Boileau E, Lin Y, Dieterich C, Förster R, Bauersachs J, Ola R, Dobreva G*, Völkers M*, Heineke J*: Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional inter-cellular communication. iScience. 2022, February 23.
Weis EM, Puchalska P, Nelson AB, Taylor J, Moll I, Hasan SS, Dewenter M, Hagenmüller M, Fleming T, Poschet G, Hotz-Wagenblatt A, Backs J, Crawford PA, Fischer A: Ketone body oxidation increases cardiac endothelial cell proliferation.
EMBO Mol Med. 2022, February 18.
Nicin L, Schroeter SM, Glaser S, Schulze-Brüning R, Pham M-D, Hille SS, Yekelchyk M, Badder K, Abplanalp WT, Tombor L, Müller OJ, Baun T, Meder B, Reich C, Arsalan M, Holubec T, Walther T, Emrich F, Krishnan J, Zeiher AM, John D, Dimmeler S: A human cell atlas of the pressure-induced hypertrophic heart. Nat Cardiovasc Res. 2022, February 14.
Xu C, Dinh VV, Kruse K, Jeong HW, Watson EC, Adams S, Berkenfeld F, Stehling M, Rasouli SJ, Fan R, Chen R, Bedzhov I, Chen Q, Kato K, Pitulescu ME, Adams RH: Induction of osteogenesis by bone-targeted Notch activation. eLife. 2022, February 4.
Wohlfeil SA, Häfele V, Dietsch B, Weller C, Sticht C, Jauch AS, Winkler M, Schmid CD, Irkens AL, Olsavszky A, Schledzewski K, Reiners-Koch PS, Goerdt S & Géraud C: Angiogenic and molecular diversity determine hepatic melanoma metastasis and response to anti-angiogenic treatment. J Transl Med. 2022, February 2.
Sivaraj KK, Majev PG, Jeong HW, Dharmalingam B, Zeuschner D, Schröder S, Bixel MG, Timmen M, Stange R, Adams RH: Mesenchymal stromal cell-derived septoclasts resorb cartilage during developmental ossification and fracture healing. Nat Commun. 2022, January 28.
Szaroszyk M, Kattih B, Martin-Garrido A, Trogisch FA, Dittrich GM, Grund G, Abouissa A, Derlin K, Meier M, Holler T, Korf-Klingebiel M, Völker K, Macedo TG, Tortola CP, Boschmann M, Huang N, Froese N, Zwadlo C, Malek Mohammadi M, Luo X, Wagner M, Cordero J, Geffers R, Batkai S, Thum T, Bork N, Nikolaev VO, Müller OJ, Katus HA, El-Amouche A, Kraft T, Springer J, Dobreva G, Wollert KC, Fielitz J, von Haehling S, Kuhn M, Bauersachs J, Heineke J: Skeletal muscle derived Musclin protects the heart during pathological overload. Nat Commun. 2022, January 10.
2021
Shen Y, Wang X, Liu Y, Singhal M, Gürkaslar C, Freire Valls A, Lei Y, Hu W, Schermann G, Adler H, Yu FX, Fischer T, Zhu Y, Augustin HG, Schmidt T, Ruiz de Almodovar C: STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis. Sci Signal. 2021, December 7.
Heil J, Olsavszky V, Busch K, Klapproth K, de la Torre C, Sticht C, Sandorski K, Hoffmann J, Schönhaber H, Zierow J, Winkler M, Schmid CD, Staniczek T, Daniels DE, Frayne J, Metzgeroth G, Nowak D, Schneider S, Neumaier M, Weyer V, Groden C, Gröne HJ, Richter K, Mogler C, Taketo MM, Schledzewski K, Géraud C, Goerdt S, Koch PS: Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation. Nat Commun. 2021 November 29.
Cai C, Itzel T, Gaitantzi H, de la Torre C, Birgin E, Betge J, Gretz N, Teufel A, Rahbari NN, Ebert MP, Breitkopf-Heinlein K: Identification of liver-derived bone morphogenetic protein (BMP)-9 as a potential new candidate for treatment of colorectal cancer. J Cell Mol Med. 2021 November 28.
Laban H, Siegmund S, Zappe M, Trogisch FA, Heineke J, Torre C, Fisslthaler B, Arnold C, Lauryn J, Büttner M, Mogler C, Kato K, Adams RH, Kuk H, Fischer A, Hecker M, Kuebler WM, Korff T: TNFAT5/TonEBP limits pulmonary vascular resistance in the hypoxic lung by controlling mitochondrial reactive oxygen species generation in arterial smooth muscle cells. Cells. 2021, November 24.
Wagner JUG, Dimmeler S: The endothelial niche in heart failure: From development to regeneration. Eur Heart J. 2021, November 1.
Friedrich M, Sankowski R, Bunse L, Kilian M, Green E, Ramallo Guevara C, Pusch S, Poschet G, Sanghvi K, Hahn M, Bunse T, Münch P, Gegner HM, Sonner JK, von Landenberg A, Cichon F, Aslan K, Trobisch T, Schirmer L, Abu-Sammour D, Kessler T, Ratliff M, Schrimpf D, Sahm F, Hopf C, Heiland DH, Schnell O, Beck J, Böttcher C, Fernandez-Zapata C, Priller J, Heiland S, Gutcher I, Quintana FJ, von Deimling A, Wick W, Prinz M, Platten M: Tryptophan metabolism drives dynamic immune-suppressive myeloid states in IDH-mutant gliomas. Nat Cancer. 2021, May 24.
Stojanovic A, Cerwenka A: ILC1-like NK cells as matchmakers for DC-T cell interactions. Immunity. 2021, October 12.
Koch PS*, Sandorski K*, Heil J, Schmid CD, Kürschner SW, Hoffmann J, Winkler M, Staniczek T, De La Torre C, Sticht C, Schledzewski K, Taketo MM, Trogisch F, Heineke J, Géraud C, Goerdt S, Olsavszky V: Imbalanced activation of Wnt-/β-catenin-signaling in liver endothelium alters normal sinusoidal differentiation. Front Physiol. 2021, September 29.
Schott J, Reitter S, Lindner D, Grosser J, Bruer M, Shenoy A, Geiger T, Mathes A, Dobreva G, Stoecklin G: Nascent Ribo-Seq measures ribosomal loading time and reveals kinetic impact on ribosome density. Nat Methods. 2021, September 3.
Singhal M*, Gengenbacher N*, Abdul Pari AA*, Kamiyama M, Hai L, Kuhn BJ, Kallenberg DM, Kulkarni SR, Camilli C, Preuß SF, Leuchs B, Mogler C, Espinet E, Besemfelder E, Heide D, Heikenwalder M, Sprick MR, Trumpp A, Krijgsveld J, Schlesner M, Hu J, Moss SE, Greenwood J, Augustin HG: Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis. Sci. Transl. Med. 2021, September 1.
Stojanovic A, Cerwenka A: An intimate encounter: DC3s empower anti-tumor CTLs. Cancer Cell. 2021, August 19.
Luck R, Karakatsani A, Shah B, Schermann G, Adler H, Kupke J, Tisch N, Jeong HW, Back MK, Hetsch F, D'Errico A, De Palma M, Wiedtke E, Grimm D, Acker-Palmer A, von Engelhardt J, Adams RH, Augustin HG, Ruiz de Almodovar C:
The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner. Cell Rep. 2021, August 17.
Kappert L, Ruzicka P, Kutikhin A, De La Torre C, Fischer A, Hecker M, Arnold C, Korff T: Loss of Nfat5 promotes lipid accumulation in vascular smooth muscle cells. FASEB J. 2021, August 12.
Jing Y, Ren Y, Witzel HR, Dobreva G: A BMP4-p38 MAPK signaling axis controls ISL1 protein stability and activity during cardiogenesis. Stem Cell Reports. 2021, August 10.
Bibli SI, Fleming I: Oxidative post translational modifications: a focus on cysteine S-sulfhydration and the regulation of endothelial fitness. Antioxid Redox Signal. 2021, August 4.
Lityagina O, Dobreva G: The LINC between mechanical forces and chromatin. Front Physiol. 2021, August 2.
Sivaraj KK, Jeong HW, Dharmalingam B, Zeuschner D, Adams S, Potente M, Adams RH: Regional specialization and fate specification of bone stromal cells in skeletal development. Cell Rep. 2021, July 13.
Alsina-Sanchis E, Mülfarth R, Fischer A: Control of tumor progression by angiocrine factors. Cancers. 2021 May 26.
Inverso D, Shi J, Lee KH, Jakab M, Ben-Moshe S, Kulkarni SR, Schneider M, Wang G, Komeili M, Argos Vélez P, Riedel M, Spegg C, Ruppert T, Schaeffer-Reiss C, Helm D, Singh I, Boutros M, Chintharlapalli S, Heikenwalder M, Itzkovitz S and Augustin HG: A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver. Developmental Cell. 2021, May 25.
Zhang XW, Huck K, Jähne K, Cichon F, Sonner JK, Ufer F, Bauer S, Woo MS, Green E, Lu K, Kilian M, Friese MA, Platten M and Sahm K: Activity-regulated cytoskeleton-associated protein/activity-regulated gene 3.1 (Arc/Arg3.1) enhances dendritic cell vaccination in experimental melanoma. Oncoimmunology. 2021, May 14.
Jiang X, Hu J, Wu Z, Cafarello ST, Di Matteo M, Shen Y, Dong X, Adler H, Mazzone M, Ruiz de Almodóvar C and Wang X: Protein Phosphatase 2A mediates YAP activation in endothelial cells upon VEGF stimulation and matrix stiffness.
Front. Cell Dev. Biol. 2021, May 13.
Nicin L, Abplanalp WT, Schänzer A, Sprengel A, John D, Mellentin H, Tombor L, Keuper M, Ullrich E, Klingel K, Dettmeyer RB, Hoffmann J, Akintuerk H, Jux C, Schranz D, Zeiher AM, Rupp S, Dimmeler S: Single nuclei sequencing reveals novel insights into the regulation of cellular signatures in children with dilated cardiomyopathy. Circulation. 2021, April 27.
Dittrich GM, Froese N, Wang X, Kroeger H, Wang H, Szaroszyk M, Malek-Mohammadi M, Cordero J, Keles M, Korf-Klingebiel M, Wollert KC, Geffers R, Mayr M, Conway SJ, Dobreva G, Bauersachs J, Heineke J: Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis. Basic Res Cardiol. 2021 April 19.
Tsedeke AT, Allanki S, Gentile A, Jimenez-Amilburu V, Rasouli SJ, Guenther S, Lai SL, Stainier DYR, Marín-Juez R: Cardiomyocyte heterogeneity during zebrafish development and regeneration. Dev Biol. 2021, April 12.
Elsherbiny A, Dobreva G: Epigenetic memory of cell fate commitment. Curr Opin Cell Biol. 2021, April 2021.
Tisch N & Ruiz de Almodóvar C: Contribution of cell death signaling to blood vessel formation. Cell Mol Life Sci. 2021 Mar 30.
Weber P, Baltus D, Jatho A, Drews O, Zelarayan LC, Wieland T & Lutz S: RhoGEF17 – An essential regulator of endothelial cell death and growth. Cells. 2021, March 27.
Koch PS*, Lee KH*, Goerdt S, Augustin HG: Angiodiversity and organotypic functions of sinusoidal endothelial cells. Angiogenesis. 2021, March 21.
Bibli SI, Hu J, Looso M, Weigert A, Ratiu C, Wittig J, Drekolia M-K, Tombor L, Randriamboavonjy V, Leisegang MS, Goymann P, Lagos FD, Fisslthaler B, Zukunft S, Kyselova A, Justo AFO, Heidler J, Tsilimigras D, Brandes RP, Dimmeler S, Papapetropoulos A, Knapp S, Offermanns S, Wittig I, Nishimura SL, Sigala F, Fleming I: Mapping the endothelial cell S-sulfhydrome highlights the crucial role of integrin sulfhydration in vascular function. Circulation. 2021, March 2.
Luxán G, Dimmeler S: The vasculature: a therapeutic target in heart failure? Cardiovasc Res. 2021, February 23.
Kohlhaas J, Jäger MA, Lust L, De La Torre C, Hecker M, Korff T: Endothelial cells control vascular smooth muscle cell cholesterol levels by regulating 24-dehydrocholesterol reductase expression. Exp Cell Res. 2021, February 15.
Olsavszky V, Sticht C, Schmid CD, Winkler M, Wohlfeil SA, Olsavszky A, Schledzewski K, Géraud C, Goerdt S, Leibing T, Koch PS: Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells. Gene. 2021, February 5.
Alsina-Sanchis E, Mülfarth R, Moll I, Mogler C, Rodriguez-Vita J and Fischer A: Intraperitoneal oil application causes local inflammation with depletion of resident peritoneal macrophages. Mol Cancer Res. 2021, February 3.
Gengenbacher N*, Singhal M*, Mogler C, Hai L, Milde L, Abdul Pari AA, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa R, Chintharlapalli SR, Augustin HG: Timed Ang2-targeted therapy identifies the Angiopoietin-Tie pathway as key regulator of fatal lymphogenous metastasis. Cancer Discov. 2021, February 2.
Winkler M, Staniczek T, Kürschner SW, Schmid CD, Schönhaber H, Cordero J, Kessler L, Mathes A, Sticht C, Neßling M, Uvarovskii A, Anders S, Zhang X, von Figura G, Hartmann D, Mogler C, Dobreva G, Schledzewski K, Géraud C, Reiners-Koch PS, Goerdt S: Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling. J Hepatol. 2021, February.
Tombor LS, John D, Glaser SF, Luxán G, Forte E, Furtado M, Rosenthal N, Baumgarten N, Schulz MH, Wittig J, Rogg EM, Manavski Y, Fischer A, Muhly-Reinholz M, Klee K, Looso M, Selignow C, Acker T, Bibli SI, Fleming I, Patrick R, Harvey RP, Abplanalp WT & Dimmeler S: Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction. Nat Commun. 2021, January 29.
Paredes I, Vieira JR, Shah B, Ramunno CF, Dyckow J, Adler H, Richter M, Schermann G, Giannakouri E, Schirmer L, Augustin HG & Ruiz de Almodóvar C: Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor–endothelial cell crosstalk. Nat Neurosci. 2021, January 28.
Morgenstern J, Fleming T, Kliemanek E, Brune M, Nawroth PP, Fischer A: Quantification of all-trans retinoic acid by liquid chromatography-tandem mass spectrometry and association with lipid profile in patients with type 2 diabetes. Metabolites. 2021, January 19.
Abdul Pari AA, Singhal M, Augustin HG: Emerging paradigms in metastasis research. J Exp Med. 2021, January 4.
Hasan SS, Fischer A: The Endothelium: An active regulator of lipid and glucose homeostasis. Trends Cell Biol. 2021, January.
Attarwala A, Hardiansyah D, Romanó C, Jiménez-Franco LD, Roscher M, Wängler B, Glatting, G: Performance assessment of the ALBIRA II pre‑clinical SPECT S102 system for 99mTc imaging. Ann Nucl Med. 2021, January.
2020
Vieira JR, Shah B, Ruiz de Almodovar C: Cellular and molecular mechanisms of spinal cord vascularization. Front Physiol. 11:599897, 2020, December 21.
Di Marco B, Crouch EE, Shah B, Duman C, Paredes MF, Ruiz de Almodovar C, Huang EJ, Alfonso J: Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon.
Cell Rep. 2020, October 13.
Wu CC, Jeratsch S, Graumann J, Stainier DYR: Modulation of mammalian cardiomyocyte cytokinesis by the extracellular matrix. Circ Res. 127:896-907, 2020, September 11.
Steiger K, Gross N, Widholz SA, Rad R, Weichert W, Mogler C: Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions. Cancers. 2020, August 13.
Jakab M, Augustin HG: Understanding angiodiversity: insights from single cell biology. Development. 2020, August 12.
Fukuda R, Marín-Juez R*, El-Sammak H*, Beisaw A, Ramadass R, Kuenne C, Guenther S, Konzer A, Bhagwat AM, Graumann J, Stainier DY: Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish. EMBO Rep. 2020, July 9.
Roider T, Seufert J, Uvarovskii A, Frauhammer F, Bordas M, Abedpour N, Stolarczyk M, Mallm J-P, Herbst SA, Bruch P-M, Balke-Want H, Hundemer M, Rippe K, Goeppert B, Seiffert M, Brors B, Mechtersheimer G, Zenz T, Peifer M, Chapuy B, Schlesner M, Müller-Tidow C, Fröhling S, Huber W, Anders S*, Dietrich S*: Dissecting intratumor heterogeneity of nodal B cell lymphomas on the transcriptional, genetic, and drug response level. Nature Cell Biology. 2020, June 15.
Abdul Pari AA*, Singhal M*, Hübers C, Mogler C, Schieb B, Gampp A, Gengenbacher N, Reynolds LE, Terhardt D, Géraud C, Utikal J, Thomas M, Goerdt S, Hodivala-Dilke K, Augustin HG# , Felcht M#: Tumor cell-derived Angiopoietin-2 promotes melanoma metastasis. Cancer Res. 80:2586-98, 2020, June 15.
Shen Y, Wang X, Lu J, Salfenmoser M, Wirsik NM, Schleussner N, Imle A, Freire Valls A, Radhakrishnan P, Liang J, Wang G, Muley T, Schneider M, Ruiz de Almodovar C, Diz-Muñoz A, Schmidt T: Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer. Cancer Cell. 2020, June 8.
Ni J, Wang X, Stojanovic A, Zhang Q, Wincher M, Bühler L, Arnold A, Correia MP, Winkler M, Koch PS, Sexl V, Höfer T, Cerwenka A: Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity. Immunity. 2020, May 22.
Ferreira C, Barros L, Baptista M, Blankenhaus B, Barros A, Figueiredo-Campos P, Konjar Š, Lainé A, Kamenjarin N, Stojanovic A, Cerwenka A, Probst HC, Marie JC, Veldhoen M: Type 1 Treg cells promote the generation of CD8+ tissue-resident memory T cells. Nat Immunol. 2020, May 18.
Ovchinnikova S, Simon A: Exploring Dimension-Reduced Embeddings With Sleepwalk. Genome Res. 30:749-56, 2020, May 18.
Nicin L, Abplanalp WT, Mellentin H, Kattih B, Tombor L, John D, Schmitto JD, Heineke J, Emrich F, Arsalan M, Holubec T, Walther T, Zeiher AM, Dimmeler S: Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts. Eur Heart J, 41:1804-6. 2020, May 14.
Singhal M, Gengenbacher N, La Porta S, Gehrs S, Shi J, Kamiyama M, Bodenmiller DM, Fischl A, Schieb B, Besemfelder E, Chintharlapalli S, Augustin HG: Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody. EMBO Mol Med. 2020, April 17.
Hasan* SS, Jabs M*, Taylor J, Wiedmann L, Leibing T, Nordström V, Federico G, Roma LP, Carlein C, Wolff G, Ekim-Üstünel B, Brune M, Moll I, Tetzlaff F, Gröne H-J, Fleming T, Géraud C, Herzig S, Nawroth PP, Fischer A: Endothelial Notch signaling controls insulin transport in muscle. EMBO Mol Med. 2020, March 18.
Gaitantzi H, Karch J, Germann L, Cai C, Rausch V, Birgin E, Rahbari N, Seitz T, Hellerbrand C, König C, Augustin HG, Mogler C, de la Torre C, Gretz N, Itzel T, Teufel A, Ebert MPA, Breitkopf-Heinlein K: BMP-9 Modulates the Hepatic Responses to LPS. Cells. 2020, March 4.
Jäger MA, De La Torre C, Arnold C, Kohlhaas J, Kappert L, Hecker M, Feldner A, Korff T: Assembly of vascular smooth muscle cells in 3D aggregates provokes cellular quiescence. Exp Cell Res. 2020, March 1.
Aslan K, Turco V, Blobner J, Sonner JK, Liuzzi AR, Núñez NG, De Feo D, Kickingereder P, Fischer M, Green E, Sadik A, Friedrich M, Sanghvi K, Kilian M, Cichon F, Wolf L, Jähne K, von Landenberg A, Bunse L, Sahm F, Schrimpf D, Meyer J, Alexander A, Brugnara G, Röth R, Pfleiderer K, Niesler B, von Deimling A, Opitz C, Breckwoldt MO, Heiland S, Bendszus M, Wick W, Becher B, Platten M: Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas. Nat Commun. 2020, February 18.
Singhal M, Augustin HG: Beyond Angiogenesis: Exploiting Angiocrine Factors to Restrict Tumor Progression and Metastasis. Cancer Res. 2020, February 15.
Glaser SF, Heumüller AW, Tombor L, Hofmann P, Muhly-Reinholz M, Fischer A, Günther S, Kokot KE, Hassel D, Kumar S, Jo H, Boon RA, Abplanalp W, John D, Boeckel JN, Dimmeler S: The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition. Proc Natl Acad Sci U S A. 2020, February 7.
Zhang XJ, Olsavszky V, Yin Y, Wang B, Engleitner T, Öllinger R, Schledzewski K, Koch PS, Rad R, Schmid RM, Friess H, Goerdt S, Hüser N, Géraud C, von Figura G, Hartmann D: Angiocrine Hepatocyte Growth Factor Signaling Controls Physiological Organ and Body Size and Dynamic Hepatocyte Proliferation to Prevent Liver Damage during Regeneration. Am J Pathol. 2020, February.
Dropmann A, Dooley S, Dewidar B, Hammad S, Dediulia T, Werle J, Hartwig V, Ghafoory S, Woelfl S, Korhonen H, Janicot M, Wosikowski K, Itzel T, Teufel A, Schuppan D, Stojanovic A, Cerwenka A, Nittka S, Piiper A, Gaiser T, Beraza N, Milkiewicz M, Milkiewicz P, Brain JG, Jones DEJ, Weiss TS, Zanger UM, Ebert M, Meindl-Beinker NM: TGF-β2 silencing to target biliary-derived liver diseases. Gut, 69:1677-90, 2020, January 21.
Sivaraj KK, Dharmalingam B, Mohanakrishnan V, Jeong HW, Kato K, Schröder S, Adams S, Koh GY, Adams RH: YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells. eLife, 9:e50770, 2020, January 20.
Bibli SI, Hu J, Leisegang MS, Wittig J, Zukunft S, Kapasakalidi A, Fisslthaler B, Tsilimigras D, Zografos G, Filis K, Brandes RP, Papapetropoulos A, Sigala F, Fleming I: Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation. Redox Biol. 2020, January 28.
Wagner JUG, Dimmeler S: Cellular cross-talks in the diseased and aging heart. J Mol Cell Cardiol. 138:136–46, 2020, January.
Wagner JUG, Pham MD, Nicin L, Hammer M, Bottermann K, Yuan T, Sharma R, John D, Muhly-Reinholz M, Tombor L, Hardt M, Madl J, Dimmeler S, Krishnan J: Dissection of heterocellular cross-talk in vascularized cardiac tissue mimetics. J Mol Cell Cardiol. 2020, January.
2019
Luck R*, Urban S*, Karakatsani A, Harde E, Sambandan S, Nicholson L, Haverkamp S, Mann R, Martin-Villalba A, Schuman EM, Acker-Palmer A, Ruiz de Almodóvar C: VEGF/VEGFR2 signaling regulates hippocampal axon branching during development. elife. 2019, December 23.
Chen Q, Liu Y, Jeong HW, Stehling M, Dinh VV, Zhou B, Adams RH: Apelin+ endothelial niche cells control hematopoiesis and mediate vascular regeneration after myeloablative injury. Cell Stem Cell, 2019, December 5.
Klose R, Prinz A, Tetzlaff F, Weis EM, Moll I, Rodriguez-Vita J, Oka C, Korff T, Fischer A: Loss of the serine protease HTRA1 impairs smooth muscle cells maturation. Scientific Reports. 2019, December 3.
Tisch N, Freire-Valls A, Yerbes R, Paredes I, La Porta S, Wang X, Martín-Pérez R, Castro L, Wong WW, Coultas L, Strilic B, Gröne HJ, Hielscher T, Mogler C, Adams RH, Heiduschka P, Claesson-Welsh L, Mazzone M, López-Rivas A, Schmidt T, Augustin HG, Ruiz de Almodovar C: Caspase-8 modulates physiological and pathological angiogenesis during retina development. J Clin Invest. 2019, December 2.
Park H, Yamamoto H, Mohn L, Ambühl L, Kanai L, Schmidt I, Kim KP, Fraccaroli A, Feil S, Junge HJ, Montanez E, Berger W* & Adams R*: Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy. Nat Commun. 2019, November 20.
Marín-Juez R, El-Sammak H, Helker CSM, Kamezaki A, Mullapuli ST, Bibli SI, Foglia MJ, Fleming I, Poss KD, Stainier DYR: Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation. Dev Cell. 2019, November 18.
Vidal R, Wagner JUG, Braeuning C, Fischer C, Patrick R, Tombor L, Muhly-Reinholz M, John D, Kliem M, Conrad T, Guimarães-Camboa N, Harvey R, Dimmeler S, Sauer S: Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart. JCI Insight. 2019, November 14.
Collins MM, Ahlberg G, Hansen CV, Guenther S, Marín-Juez R, Sokol AM, El-Sammak H, Piesker J, Hellsten Y, Olesen MS, Stainier DYR: Lundegaard PR: Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model. Proc Natl Acad Sci U S A. 2019, November 8.
Gancz D, Raftrey BC, Perlmoter G, Marín-Juez R, Semo J, Matsuoka RL, Karra R, Raviv H, Moshe N, Addadi Y, Golani O, Poss KD, Red-Horse K, Stainier DY, Yaniv K: Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration. elife. 2019, November 8.
Freire Valls A*, Knipper K*, Giannakouri E, Sarachaga V, Hinterkopf S, Wuehrl M, Shen Y, Radhakrishnan P, Klose J, Ulrich A, Schneider M, Augustin HG, Ruiz de Almodovar C, Schmidt T: VEGFR1+ Metastasis-Associated Macrophages Contribute to Metastatic Angiogenesis and Influence Colorectal Cancer Patient Outcome. Clin Cancer Res. 2019, September 15.
Malek Mohammadi M, Abouissa A, Azizah I, Xie Y, Cordero J, Shirvani A, Gigina A, Engelhardt M, Trogisch FA, Geffers R, Dobreva G, Bauersachs J, Heineke J: Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation. JCI Insight. 2019, July 23.
Siragusa M, Thöle J, Bibli SI, Luck B, Loot AE, Silva K de, Wittig I, Heidler J, Stingl H, Randriamboavonjy V, Kohlstedt K, Brüne B, Weigert A, Fisslthaler B, Fleming I: Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition. EMBO J. 2019, July 22.
Scharf GM, Kilian K, Cordero J, Wang Y, Grund A, Hofmann M, Froese N, Wang X, Kispert A, Kist R, Conway SJ, Geffers R, Wollert KC, Dobreva G, Bauersachs J, Heineke J: Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation. JCI Insight. 2019, July 16.
Gao R, Liang X, Cheedipudi S, Cordero J, Jiang X, Zhang Q, Caputo L, Günther S, Kuenne C, Ren Y, Bhattacharya S, Yuan X, Barreto G, Chen Y, Braun T, Evans SM, Sun Y, Dobreva G: Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate. Cell Res. 2019, June.
Schreiber C, Saraswati S, Harkins S, Gruber A, Cremers N, Thiele W, Rothley M, Plaumann D, Korn C, Armant O, Augustin HG, Sleeman JP: Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling. PLoS Genet. 2019, June 27.
Lai SL, Marín-Juez R, Stainier DYR: Immune responses in cardiac repair and regeneration: a comparative point of view.
Cell Mol Life Sci. 2019, April 15.
Karakatsani A, Shah B, Ruiz de Almodovar C: Blood vessels as regulators of neural stem cell properties. Front Mol Neurosci. 2019, April 12.
Wohlfeil SA*, Häfele V*, Dietsch B, Schledzewski K, Winkler M, Zierow J, Leibing T, Mohammadi MM, Heineke J, Sticht C, Olsavszky V, Koch PS, Géraud C*, Goerdt S*: Hepatic endothelial Notch activation protects against liver metastasis by regulating endothelial-tumor cell adhesion independent of angiocrine signaling. Cancer Res. 2019, February 1.
Bibli SI*, Hu J*, Sigala F, Wittig I, Heidler J, Zukunft S, Tsilimigras D, Randriamboavonjy V, Wittig J, Kojonazarov B, Schürmann C, Siragusa M, Siuda D, Luck B, Abdel Malik R, Filis K, Zografos G, Chen C, Wang DW, Pfeilschifter J, Brandes RP, Szabo C, Papapetropoulos A, Fleming I: Cystathionine γ lyase sulfhydrates the RNA binding protein HuR to preserve endothelial cell function and delay atherogenesis. Circulation. 2019, January 2.
Grund A, Szaroszyk M, Doppner JK, Malek Mohammadi M, Kattih B, Korf-Klingebiel M, Gigina A, Scherr M, Kensah G, Jara-Avaca M, Gruh I, Martin U, Wollert KC, Gohla A, Katus HA, Muller OJ, Bauersachs J, Heineke J: A gene therapeutic approach to inhibit calcium and integrin binding protein 1 ameliorates maladaptive remodelling in pressure overload. Cardiovasc Res. 2019, January 1.
