Junior Research Group Leader
European Center for Angioscience
Medical Faculty Mannheim, Heidelberg University
2016 - 2021
Max Planck Institute for Heart and Lung Research
Bad Nauheim, Germany
University of Ulm, Germany
Bertozzi A, Wu CC, Hans S, Brand M, Weidinger G: Wnt/β-catenin signaling acts cell-autonomously to promote cardiomyocyte regeneration in the zebrafish heart. Dev Biol, 481:226-37, 2022.
Bertozzi A*, Wu CC*, Dalvoy M, Nguyen P, Koopman C, de Boer T, Bakkers J, Weidinger G: Is zebrafish heart regeneration ‘complete’? Lineage-restricted cardiomyocytes proliferate to pre-injury numbers but some fail to differentiate in fibrotic hearts. Dev Biol, 471:106-18, 2021. (*equal contribution)
Wu CC#, Jeratsch S, Graumann J, Stainier DYR#: Modulation of mammalian cardiomyocyte cytokinesis by the extracellular matrix. Circ Res, 127:896-907, 2020. (#Corresponding authors)
Beisaw A, Kuenne C, Günther S, Dallmann S, Wu CC, Bentsen M, Looso B, Stainier DYR: AP-1 contributes to chromatin accessibility to promote sarcomere disassembly and cardiomyocyte protrusion during zebrafish heart regeneration. Circ Res, 126:1760-78, 2020.
Wu CC*, Kruse F*, Dalvoy M, Junker JP, Zebrowski DC, Fischer K, Noël ES, Grün D, Berezikov E, Engel FB, van Oudenaarden A, Weidinger G, Bakkers J: Spatially-resolved genome-wide transcriptional profiling identifies BMP signaling as essential regulator of zebrafish cardiomyocyte regeneration. Dev Cell, 36:36-49, 2016. (*equal contribution)
Wu CC, Weidinger G: Cardiac regeneration in zebrafish Regenerative Medicine: from Protocol to Patient – Biology of Tissue Regeneration, 3rd edition:307-37, 2016.
Zebrowski DC, Vergarajauregui S, Wu CC, Piatkowski T, Becker R, Leone M, Hirth S, Ricciardi F, Falk N, Giessl A, Just S, Braun T, Weidinger G, Engel FB: Developmental alterations in centrosome integrity contribute to the post-mitotic state of mammalian cardiomyocytes. eLife, 4:e05563, 2015.
Wu CC, Weidinger G: Zebrafish as a model for studying cardiac regeneration. Curr Pathobiol Rep, 2:93-100, 2014.
Schnabel K*, Wu CC*, Kurth T, Weidinger G: Regeneration of cryoinjury induced necrotic heart lesions in zebrafish is associated with epicardial activation and cardiomyocyte proliferation. PLoS One, 6:e18503, 2011. (*equal contribution)
Chan WM, Tsoi H, Wu CC, Wong CH, Cheng TC, Li HY, Lau KF, Shaw PC, Perrimon N, Chan HYE: Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. Hum Mol Genet, 20:1738-50, 2011.