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CRC1366

Vascular Control of Organ Function

Dr. Simon Anders

Center for Molecular Biology, Heidelberg

Professional Career

Since 2017

Project Group Leader

Center for Molecular Biology (ZMBH)

Heidelberg University, Germany

2015 - 2017

Group Leader

Institiute for Molecular Medicine (FIMM)

University of Helsinki, Finland

2011 - 2015

Research Scientist

European Molecular Biology Laboratory (EMBL)

Heidelberg, Germany

2009 -2011

Post-doctoral Fellow

European Molecular Biology Laboratory (EMBL), Heidelberg

2007 -2009

Post-doctoral Scientist

European Bioinformatics Institute (EMBL-EBI)

Hinxton, Cambridge, UK

2003 - 2007

Ph.D.

in Theoretical Physics, University of Munich (LMU), Germany

and University of Innsbruck, Austria

Selected Publications

Wang ZY, Leushkin E, Liechti A, Ovchinnikova S, Mößinger K, Brüning T, Rummel C, Grützner F, Cardoso-Moreira M, Janich P, Gatfield D, Diagouraga B, de Massy B, Gill ME, Peters AHFM, Anders S, Kaessmann H: Transcriptome and translatome co-evolution in mammals. Nature. 588:642-647, 2020.

Dao Thi VL, Herbst K, Boerner K, Meurer M, Kremer LP, Kirrmaier D, Freistaedter A, Papagiannidis D, Galmozzi C, Stanifer ML, Boulant S, Klein S, Chlanda P, Khalid D, Barreto Miranda I, Schnitzler P, Kräusslich HG, Knop M, Anders S: A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples. Sci Transl Med. 12:eabc7075, 2020.

Roider T, Seufert J, Uvarovskii A, Frauhammer F, Bordas M, Abedpour N, Stolarczyk M, Mallm JP, Herbst SA, Bruch PM, Balke-Want H, Hundemer M, Rippe K, Goeppert B, Seiffert M, Brors B, Mechtersheimer G, Zenz T, Peifer M, Chapuy B, Schlesner M, Müller-Tidow C, Fröhling S, Huber W, Anders S, Dietrich S: Dissecting intratumour hetero-geneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels. Nat Cell Biol. 22:896-906, 2020.

Ovchinnikova S, Anders S: Exploring dimension-reduced embeddings with Sleepwalk. Genome Res. 30:749-756, 2020.

Cardoso-Moreira M, Halbert J, Valloton D, Velten B, Chen C, Shao Y, Liechti A, Ascenção K, Rummel C, Ovchinnikova S, Mazin PV, Xenarios I, Harshman K, Mort M, Cooper DN, Sandi C, Soares MJ, Ferreira PG, Afonso S, Carneiro M, Turner JMA, VandeBerg JL, Fallahshahroudi A, Jensen P, Behr R, Lisgo S, Lindsay S, Khaitovich P, Huber W, Baker J, Anders S, Zhang YE, Kaessmann H: Gene expression across mammalian organ development. Nature. 571:505-509, 2019.

Kalamakis G, Brüne D, Ravichandran S, Bolz J, Fan W, Ziebell F, Stiehl T, Catalá-Martinez F, Kupke J, Zhao S, Llorens-Bobadilla E, Bauer K, Limpert S, Berger B, Christen U, Schmezer P, Mallm JP, Berninger B, Anders S, Del Sol A, Marciniak-Czochra A, Martin-Villalba A: Quiescence modulates stem cell maintenance and regenerative capacity in the aging brain. Cell. 176:1407-1419.e14, 2019.

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M: Orchestrating high-throughput genomic analysis with Bioconductor. Nat Methods. 12:115-21, 2015.

Anders S, Pyl PT, Huber W: HTSeq-a Python framework to work with high-throughput sequencing data. Bioinformatics. 31:166-9, 2015.

Love MI, Huber W, Anders S: Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 15(12):550, 2014.

Brennecke P, Anders S, Kim JK, Kołodziejczyk AA, Zhang X, Proserpio V, Baying B, Benes V, Teichmann SA, Marioni JC, Heisler MG: Accounting for technical noise in single-cell RNA-seq experiments. Nat Methods. 10:1093-5, 2013.

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