CRC1366
Vascular Control of Organ Function
Past Seminars
InSight Seminars
2026
Birthe Lemke
Subtyping endothelial cell states in primary and relapsed glioblastoma using single-cell spatially
resolved transcriptomic (Xenium In Situ)
and
Dr. Marco Sachse
RNA editing controls polyvascular disease by enhancing metabolic inflammation
and
Ricarda Meryem Cemile Remus
Role of Rnd3 in sinusoidal endothelial cells during liver development and maturation
Wednesday, May 20, 2026
Lea Sophie Götz
Functional characterization of the novel Id protein inhibitor X6632 in preclinical models of
cancer and (lymph)angiogenesis
and
Dr. Yohanes Wibowo
The role of EPAC-1 in tumor-related angiogenesis
Wednesday, April 15, 2026
Emma Reynaud
Investigating the contribution of lymphatic PD-L1 on immune regulation in melanoma-draining
lymph node
and
Dr. Dennis Alexander Agardy
Perivascular immune cell niches in glioma
Wednesday, March 11, 2026
Dr. Miki Kamiyama
Tie1 ectodomain cleavage governs the vascular response to inflammatory stimulation
and
Dr. Maria Llamazares Prada
and
David Rodriguez Morales
Vascular niches are the primary hotspots in cardiac aging
Wednesday, February 11, 2026
Sabrina Kaminsky
The ECM as a regulator of chamber-specific cardiomyocyte polyploidization
and
Dr. Marius Roland Hardt
When skin meets liver: Endothelial and immune drivers of Psoriasis-associated hepatopathy
Wednesday, January 28, 2026
2025
Dr. Qaaifah Gillani Syed
Investigating the role of Rab24 in mitochondrial regulation
and
Prof. Christian Schulz
Reticulated platelets as drivers of recurrent thrombosis
Wednesday, December 3, 2025
Hannah Pauline Nehring
The LSEC-immune interface in the liver
and
Dr. Tom Kretzschmar
EC metabolite-mediated control of vascular remodelling in the Hypoxia-exposed lung
Wednesday, November 5, 2025
Loss of Smad4 drives vascular malformations via c-KIT-dependent high shear stress mimicry
Wednesday, October 8, 2025
Dr. Melina Hußmann
Angiopoietin 2 regulates metabolic health during aging
and
Maria-Kyriaki Drekolia
Ferroptosis governs lymphatic vessel growth and regression
Wednesday, July 2, 2025
Yanliang Dou
RNF20 at the nexus of angiocrine signaling in the pathogenesis of heart disease
and
Max Hüllwegen
Effects of recombinant GDF15 on endothelial cells
Wednesday, June 4, 2025
Dr. Michael Amponsah-Offeh
Endothelial immunomodulation in cardiometabolic disease
and
Dr. Bhavin Shah
Role of Rnd3 in LSECs during liver development
Wednesday, May 8, 2025
Lea Gärtner
Anti-cancer and anti-(lymph)angiogenic effects of targeting the transcriptional regulators ID1
and ID3
and
Dr. Nicolas Schommer
Platelet C5aR1 drives cardiac injury through platelet–neutrophil interactions and NETs
Wednesday, April 2, 2025
Emma Reynaud
Impact of lymphatic PD-L1 on immune landscapes in melanoma
Wednesday, March 5, 2025
Vascular niche in the ageing heart
and
Lorna Wessels
Informed gene clustering based on upstream regulators
Wednesday, February 5, 2025
Tian Lan
Endothelial regulation of cardiomyocyte polyploidization
and
Theresa Deutschmann
The role of transcriptional regulator Meis2 in sinusoidal endothelial cells during liver
development and maturation
Wednesday, January 15, 2025
2024
Riham Rafea and Dr. Mauro Siragusa
Nuclear eNOS interacts with and S-nitrosates ADAR1 to modulate type I interferon signalling
and endothelial function
Wednesday, December 11, 2024
Dr. Rhys Wardman
Collagen I is a novel RNA binding protein: Uncovering the role of its interactions with RNA
and
Johannes Gahn
The role of Smad signaling in maintaining hemodynamic homeostasis
Wednesday, November 13, 2024
Nalan Tetik
RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth
and
Dr. Elisenda Alsina Sanchis
Endothelial RBPJ plays a role in immune cell differentiation
Wednesday, September 18, 2024
Pallavi Pant
Evidences of an Endothelial –Astrocyte – Neuron axis instructing neurodevelopment
Wednesday, May 8, 2024
Dr. Reinhard Sauter
Anaphylatoxin receptor C3aR contributes to platelet function, thrombus formation and
in vivo haemostasis
and
Dr. Malarvizhi Gurusamy
Function of endothelial S1PR1 during postnatal bone development
Wednesday, March 6, 2024
Sophia Knecht
Influence of RND3 of sinusoidal endothelial differentiation and scavenging function
and
Kathleen Schlüter
Studying spatial biology with Multiplexed Ion Beam Imaging
Wednesday, February 14, 2024
2023
Stephanie Preuß
Systemic vascular reprogramming regulates cancer cachexia
and
Dr. Rhys Wardman
RNA-binding proteins regulate post-transcriptional responses to TGF-β to coordinate function and
mesenchymal activation of murine endothelial cells
Wednesday, December 6, 2023
Lea Sophie Gärtner
Targeting the transcriptional regulators Id1 and Id3 in melanoma: characterization of the novel
inhibitor X6632
and
Emma Reynaud
Lymphatic endothelial regulation of immune responses in the lymph node microenvironment
Wednesday, October 11, 2023
Dr. Felix Trogisch
The fibrogenic transcription factor Sox9 controls mesenchymal activation of endothelial cells and
drives fibrotic disease
and
Dennis Agardy
Perivascular T cell niches in gliomas
Wednesday, September 13, 2023
Dr. Manuel Winkler
Molecular regulation of hepatic angiodiversity and liver fibrosis by GATA4 and MAF
and
Prof. Iris Bibli
The role of CSE in endothelial cell aging
Wednesday, July 12, 2023
Dr. Pooja Sagvekar
Investigation of endocardium derived factors influencing cardiomyocyte regeneration dynamics in zebrafish
and
Giorgia Ciliberti
The role of ADAR2 in atherosclerosis and vascular inflammation
Wednesday, June 7, 2023
Nalan Tetik
RNF20-mediated transcriptional pausing and alternative splicing of pro-angiogenic genes orchestrate vessel growth
and
Francesco Cortopassi
Fine-tuning of NK cell responses by the HIF-1α–AhR pathway
Wednesday, May 10, 2023
Dr. Sana Safatul Hasan
Obesity drives depot-specific vascular remodeling in white adipose tissue
and
Dr. Miki Kamiyama
Cleavage of Tie1 ectodomain sensitizes vasculature to inflammatory insults
Wednesday, April 5, 2023
Kuheli Banerjee
SMAD4 maintains the fluid shear stress set point to protect against arterial-venous malformations
and
Shanshan Zhang
Platelet-specific C5a receptor (C5aR) 1 deficiency improves cardiac function in a mouse model of acute myocardial infarction
Wednesday, March 8, 2023
Dr. Thomas Leibing
New insights into the role of LSEC-mediated scavenging of fasciclin domain proteins
and
Dr. Seyed Javad Rasouli
Organ-specific specialization and functional heterogeneity of pericytes
Wednesday, February 8, 2023
Prof. Carmen Wängler
Development of radiopharmaceuticals: From basic science to application
and
José Ricardo da Cruz Vieira
Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development
Wednesday, January 11, 2023
2022
Steve Grein
Stress-induced lncRNA Lockd modulates angiogenesis and proliferation of endothelial cells
Wednesday, December 7, 2022
Moritz Jakab
Vascular control of metastatic fates
and
Lucas Tombor
Dynamic endothelial states after myocardial infarction
and
Stephanie Gehrs
Distal regulatory elements control the angiogenic and homeostatic endothelial state
Wednesday, November 9, 2022
Dr. Nirmeen Elmadany
Fractionated irradiation boosts antigen-specific T-cell response in malignant glioma via enhancing leukocyte-endothelial interactome
2021
Dr. Carolin Mogler
Histological spectrum of liver lesions in rodent models for liver tumorigenesis
and
Merve Keles
Deletion of long non-coding RNAs GADLOR1 and GADLOR2 preserves cardiac function during pressure overload
and
Dr. Nirmeen Elmadany
Investigating molecular targets in glioma-derived endothelial cells for a better response to immunotherapy
Wednesday, December 1, 2021, ONLINE via Cisco Webex Meetings
Dr. Sonja Thaler
Therapy resistance mechanisms in estrogen receptor-positive breast cancer
and
Prof. Thomas Korff
Coping with hypoxic stress - Adjustsment of cellular transcription in pulmonary arteries by NFAT5
Wednesday, November 17, 2021, ONLINE via Cisco Webex Meetings
Dr. Ashik Ahmed Abdul Pari
Vascular aging limits metastasis
and
Dr. Katharina Schlereth
DNMT3A-dependent DNA methylation ensures
endothelial cell function in development and aging
Wednesday, October 6, 2021, Tridomus, House B, S43, Mannheim & online
Dr. Katja Breitkopf-Heinlein
Differential BMP-9/ALK1 signalling outcome in human
endothelial and epithelial cell types of gut and liver
and
Lukas Tombor
Endothelial plasticity after myocardial infarct
Wednesday, July 7, 2021, ONLINE via Cisco Webex Meetings
Prof. Iris-Sofia Bibli
Endothelial de-CYS-tiny: Cysteinolysis and endothelial cell fates
and
Dr. Victor Olsavszky
Activating β-Catenin mutation in bone marrow sinusoidal endothelium leads to dyserythropoiesis
Wednesday, June 16, 2021, ONLINE via Cisco Webex Meetings
Hadil El-Sammak
Vegfc signaling promotes coronary revascularization during cardiac regeneration in zebrafish
and
Yohanes Wibowo
The cyclic AMP effector Epac1 is a main endothelial
signaling hub
and
Dr. Felix Trogisch
Endothelial Sox9 Is A Master Regulator of Cardiac Fibrosis and Maladaptive Remodeling
Wednesday, May 5, 2021, ONLINE via Cisco Webex Meetings
Dr. Ana Stojanovic
Immuno-endothelial cross-talk in the liver
and
Nalan Tetik-Elsherbiny
The role of RNF20 in Vascular Development
Wednesday, April 14, 2021, ONLINE via Cisco Webex Meetings
Dr. Alexey Uvarovskii
Analysis of spatial expression patterns in hepatocytes and endothelial cells
and
Dr. Nathalie Tisch
Casp8 in endothelial cells is required to maintain intestine homeostasis
and
Dr. Natalia Kuch
Photobiomodulation – Influence of blue light on skin cells
Wednesday, March 3, 2021, ONLINE via Cisco Webex Meetings
Dr. Jacqueline Taylor
Fat wasting in cancer: the role of endothelial Notch1 signaling
and
Kuheli Banerjee
Kruppel-like factor 4 (KLF4) is a key determinant in arteriovenous malformation (AVM) pathogenesis
Wednesday, February 3, 2021, ONLINE via Cisco Webex Meetings
Dr. Seyed Javad Rasouli
Organ-specific specialization and functional heterogeneity of pericytes
and
Dr. Thomas Leibing
Systemic atheroprotection by Stabilin1/2 inhibition
Wednesday, January 13, 2021, ONLINE via Cisco Webex Meetings
2020
Dr. Hebatullah Laban
Endothelial NFAT5-dependent control of lung hypoxia responses
and
Jihong Lin
microRNA-124a prevents retinal vasoregression in PKD rats
Wednesday, December 2, 2020, ONLINE via Cisco Webex Meetings
Dr. Katrin Huck
Vascular control of tumor immunity in the central nervous system
and
Dr. Haristi Gaitantzi
Generation of Human Organoids from adult, normal or malignant Tissue
Wednesday, November 4, 2020, ONLINE via Cisco Webex Meetings
Dr. Katharina Schlereth
Aging-associated epigenetic changes in endothelial cells
and
Sarah Wahby
Investigation of extracellular matrix-dependent mechanisms by multiomics Analysis of bladder Cancer 3D in vitro mode
Wednesday, October 7, 2020, ONLINE via Cisco Webex Meetings
Kaixuan Yan
Influence of ABC5+ mesenchymal stem cells on hypoxic damage in vitro and in vivo
and
Dr. Miki Kamiyama
Endothelial lipidome/transcriptom profile during tumor progression
Wednesday, June 3, 2020, ONLINE via Cisco Webex Meetings
Dr. Kay Klapproth
Delineating ontogenic and functional heterogeneity of tissue macrophages
and
Dr. Caroline Schreiber
Physiological and pathophysiological roles of ASAP1
Wednesday, May 6, 2020, ONLINE via Cisco Webex Meetings
Anna Jauch
Role of Lyve-1 during hepatic metastatis of malignant melanoma
and
PD Dr. Walter Muranyi
A human in vitro model of the blood-cerebrospinal fluid barrier to study endo-epithelial as well as host-pathogen interaction
Wednesday, March 4, 2020, Tridomus, House B, S41, Mannheim
2019
Mahak Singhal
Angiocrine regulation of metastatic progression
and
Jia-Xiang See
Liver sinusoidal endothelial cell-mediated control of innate lymphoid cell function
Wednesday, November, 2019, Tridomus, House B, S41, Mannheim
Rui Gao
Pioneering function of Isl1 in epigenetic regulation during second heart field development
and
Nalan Tetik
The role of RNF20 in vascular function
Wednesday, November, 2019, Tridomus, House B, S41, Mannheim
Eva-Maria Weis
Ketone bodies induce endothelial cell proliferation
and
Haristi Gaitantzi
Generation of human liver organoids
Wednesday, October, 2019, Tridomus, House B, S41, Mannheim
Dr. Prama Pallavi
Influence of Mesenchymal Stem Cells on HUVEC: Potential Impact for Chronic Limb Ischemia
and
Nicolas Gengenbacher
Targeting Angiopoietin-2 in Advanced Models of Metastasis
Wednesday, July 3, 2019, 12 pm, Tridomus, House B, Room S41, Mannheim
Dr. Georg Sedlmeier
Sleeman Group
Id proteins as therapeutic targets in cancer
Wednesday, June 5, 2019, 12 pm, Tridomus, House B, Ebene 2, Room S41
Ludolf-Krehl-Str. 7-11, 68167 Mannheim
Dr. Katharina Schlereth
Epigenetic remodeling is essential for postnatal angiogenesis
and
Dr. Victor Olsavszky
Angiocrine HGF signaling in the liver
Wednesday, May 8, 2019, 12 pm, Tridomus, House B, Room S43, Mannheim
Wednesday, May 8, 2019, Tridomus, House B, Room S43, Ebene 2
PD Dr. Katja Breitkopf-Heinlein
How BMP-9 modulates the hepatic responses to LPS
and
Dr. Manuel Winkler - AG Goerdt/Koch
Gata4 - master regulator of organ-specific endothelial
specification in the liver
Wednesday, April 3, 2019, 12 pm, Tridomus, House B, Room S41, Mannheim
Dr. Anupriya Chatterjee - AG Feng / Wieland
The Role of O-GlcNAcylation in NDPK-B Deficiency-Correlated Endothelial Damage
and
Dr. Matthias Kolibabka - AG Hammes
Impact of Endothelial Gene Regulation on the Cell-cell communication of the Neurovascular Unit
Wednesday, March 6, 2019, 12 pm, Tridomus, House B, Room S4, Mannheim1
Dr. Donato Inverso - AG Augustin
Angiopoietin-Tie Regulation of Organo-specific Angiocrine Wnt Codes
and
Dr. Andromachi Karakatsani - AG Ruiz de Almodóvar
Neurovascular Link in Neurogenic Niches of the Adult Mouse Brain
Wednesday, Feb. 6, 2019, 12 pm, Tridomus, House B, Room S41, Mannheim