CRC1366

Gaitantzi H, Karch J, Germann L, Cai C, Rausch V, Birgin E, Rahbari N, Seitz T, Hellerbrand C, König C, Augustin HG, Mogler C, de la Torre C, Gretz N, Itzel T, Teufel A, Ebert MPA, Breitkopf-Heinlein K: BMP-9 Modulates the Hepatic Responses to LPS. Cells, 9:617, 2020.

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Aghamaliyev U, Gaitantzi H, Thomas M, Simon-Keller K, Gaiser T, Marx A, Yagublu V, Araos J, Cai C, Valous NA, Halama N, Kiesslich T, Ebert M, Grützmann R, Rückert F, Breitkopf-Heinlein K: Downregulation of SPARC Is Associated with Epithelial-Mesenchymal Transition and Low Differentiation State of Biliary Tract Cancer Cells. Eur Surg Res, 60:1-12, 2019.

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Gaitantzi H, Meyer C, Rakoczy P, Thomas M, Wahl K, Wandrer F, Bantel H, Alborzinia H, Wölfl S, Ehnert S, Nüssler A, Bergheim I, Ciuclan L, Ebert M, Breitkopf-Heinlein K, Dooley S: Ethanol sensitizes hepatocytes for TGF-β- triggered apoptosis. Cell Death Dis, 9:51, 2018.

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Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans M, Hawinkels LJAC, Lee S, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, tenDijke P. BMP-9 interferes with liver regeneration and promotes liver fibrosis. Gut, 66:939-54, 2017

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Koch PS, Olsavszky V, Ulbrich F, Sticht C, Demory A, Leibing T, Henzler T, Meyer M, Zierow J, Schneider S, Breitkopf-Heinlein K, Gaitantzi H, Spencer-Dene B, Arnold B, Klapproth K, Schledzewski K, Goerdt S, Géraud C. Angiocrine Bmp2 signaling in murine liver controls normal iron homeostasis. Blood. 2017;129:415-9.

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Ramachandran SD, Schirmer K, Münst B, Heinz S, Ghafoory S, Wölfl S, Simon-Keller K, Marx A, Øie CI, Ebert MP, Walles H, Braspenning J, Breitkopf-Heinlein K. In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells. PLoS One,10:e0139345, 2015.

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Gobejishvili L*, Barve S*, Breitkopf-Heinlein K*, Li Y, Zhang J, Avila DV, Dooley S, McClain CJ. Rolipram attenuates bile duct ligation-induced liver injury in rats: a potential pathogenic role of PDE4. J Pharmacol Exp Ther. 347:80-90, 2013 (*KB-H, LG and SB contributed equally).

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Li Q, Gu X, Weng H, Ghafoory S, Liu Y, Feng T, Dzieran J, Li L, Ilkavets I, Kruithof-de Julio M, Munker S, Marx A, Piiper A, Augusto Alonso E, Gretz N, Gao C, Wölfl S, Dooley S, Breitkopf-Heinlein K. Bone morphogenetic protein-9 induces epithelial to mesenchymal transition in hepatocellular carcinoma cells. Cancer Sci. 104:398-408, 2013

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Ciuclan L, Ehnert S, Ilkavets I, Weng H-L, Gaitantzi H, Tsukamoto H, Ueberham E, Singer MV, Breitkopf K*, Dooley S*. TGF-β enhances alcohol dependent hepatocyte damage via down regulation of alcohol dehydrogenase I. J. Hepatol, 52:407-16, 2009 (*KB and SD contributed equally).

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Wiercinska E, Wickert L, Denecke B, Said HM, Hamzavi J, Gressner AM, Thorikay M, ten Dijke P, Mertens PR, Breitkopf K*, Dooley S*. Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells. Hepatology, 43:1032-41, 2006 (*KB and SD contributed equally).