Simon_Anders.jpg

Dr. Simon Anders

Project Z3

 

Center for Molecular Biology, Heidelberg

 

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s.ander(at)zmbh.uni-heidelberg.de

Simon Anders obtained his PhD at the University of Innsbruck. He then moved to the European Bioinformatics Institute in Hinxton and to the group of Wolfgang Huber at the European Molecular Biology Laboratory in Heidelberg to pursue postdoctoral training, before setting up his own group at the , Institute for Molecular Medicine Finland. Now he is Project Group Leader at the Centre for Molecular Biology at Heidelberg University. 

Qualifications and Scientific Curriculum

PhD Student, Institute for Theoretical Physics, University of Munich (LMU)

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PhD Student, Institute for Theoretical Physics, University of Innsbruck, Austria

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Postdoctoral Scientist, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge, UK

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Postdoctoral Fellow, European Molecular Biology Laboratory (EMBL), Heidelberg

 

Research Scientist, European Molecular Biology Laboratory (EMBL), Heidelberg

 

Group Leader, Institute for Molecular Medicine Finland (FIMM), University of Helsinki

 

Project Group Leader, Centre for Molecular Biology (ZMBH), University of Heidelberg

2003

2004-2007

2007-2009

2009-2011

2011-2015

2015-2017

since 2017

Selected publications

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  1. Roider T, Seufert J, Uvarovskii A, Frauhammer F, Bordas M, Abedpour N, Stolarczyk M, Mallm JP, Herbst SA, Bruch PM, Balke-Want H, Hundemer M, Rippe K, Goeppert B, Seiffert M, Brors B, Mechtersheimer G, Zenz T, Peifer M, Chapuy B, Schlesner M, Müller-Tidow C, Fröhling S, Huber W, Anders S*, Dietrich S*: Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels. Nat Cell Biol, 22:896-906, 2020.

  2. Cardoso-Moreira M, Halbert J, Valloton D, Velten B, Chen C, Shao Y, Liechti A, Ascenção K, Rummel C, Ovchinnikova S, Mazin PV, Xenarios I, Harshman K, Mort M, Cooper DN, Sandi C, Soares MJ, Ferreira PG, Afonso S, Carneiro M, Turner JMA, VandeBerg JL, Fallahshahroudi A, Jensen P, Behr R, Lisgo S, Lindsay S, Khaitovich P, Huber W, Baker J, Anders S, Zhang YE, Kaessmann H: Gene expression across mammalian organ development. Nature, 571:505-509, 2019.

  3. Kalamakis G, Brüne D, Ravichandran S, Bolz J, Fan W, Ziebell F, Stiehl T, Catalá-Martinez F, Kupke J, Zhao S, Llorens-Bobadilla E, Bauer K, Limpert S, Berger B, Christen U, Schmezer P, Mallm JP, Berninger B, Anders S, Del Sol A, Marciniak-Czochra A, Martin-Villalba A: Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain. Cell, 176:1407-1419, 2019.

  4. Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M: Orchestrating high-throughput genomic analysis with Bioconductor. Nat Methods, 12:115, 2015.

  5. Love M, Anders S, Kim V, Huber W: RNA-Seq workflow: gene-level exploratory analysis and differential expression. F1000 Research, 4:1070, 2015.

  6. Anders S, Pyl PT, Huber W:  HTSeq – A Python framework to work with high-throughput sequencing data. Bioinformatics, 31:166, 2015.

  7. Love MI, Huber W, Anders S:  Moderated estimation of fold change and dispersion for RNA-Seq data with DESeq2. Genome Biol, 15:550, 2014.

  8. Brennecke P, Anders S, Kim JK, Kołodziejczyk AA, Zhang X, Proserpio V, Baying B, Benes V, Teichmann SA, Marioni JC, Heisler MG: Accounting for technical noise in single-cell RNA-seq experiments. Nat Methods, 10:1093, 2013.

  9. Anders S*, Reyes A*, Huber W: Detecting differential usage of exons from RNA-seq data. Genome Research, 22:2012.

  10. Anders S, Huber W: Differential expression analysis for sequence count data. Genome Biol, 11:R106, 2010.