Associated Member since 07/20 | Project

CardioVascular Pharmacology, Experimental Pharmacology 

European Center for Angioscience (ECAS)
Medical Faculty Mannheim Heidelberg University

 

roxana.ola(at)medma.uni-heidelberg.de

Roxana Ola 

- under construction -

Qualifications and Scientific Curriculum

since 2020

Junior Professor of CardioVascular Pharmacology Dept. of Experimental Pharmacology group, Medical Faculty Mannheim, Heidelberg University, Germany

            - under construction -

Selected publications

  1. Genet G, Boyé K, Mathivet T, Ola R, Zhang F, Dubrac A, Li J, Genet N, Henrique Geraldo L, Benedetti L, Künzel S, Pibouin-Fragner L, Thomas JL, Eichmann A: Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis. Nat Commun. 10:2350, 2019.

  2. Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel S,  Camporez JP, Singh AK, Fong GH, Simons M, Tso P, Hernando CF, Shulman GI, Sessa WC, Eichmann A: Lacteal junction zippering protects against diet-induced obesity. Science. 361:599-603, 2018.

  3. Ola R, Künzel SH, Zhang F, Genet G, Chakraborty R, Fragner LP, Martin K, Sessa W, Dubrac A, Eichmann A: SMAD4 prevents flow induced arterial-venous malformations by inhibiting Casein Kinase 2. Circulation. 138:2379-2394, 2018

  4. Lee HW* Chong D*, Ola R* Dunworth WP, Meadows S, Ka J, Kaartinen V, Qyang Y, Cleaver O,  Bautch V, Eichmann A, Jin SW: Distinct requirement of Alk2/ACVR1 and Alk3/BMPR1A in bone morphogenetic protein induced retinal angiogenesis. Arterioscler Thromb Vasc Biol. 37:657-663, 2017 (*LHW, CD and OR contributed equally).

  5. Ola R, Dubrac A, Han J, Fang JS, Zhang F,  Larrivée B, Lee M, Urarte AA, Kraehling JR, Genet G, Hirschi KK, Sessa WC, Canals V, Graupera M, Yan M, Young LH, Oh SP, Eichmann A: PI3 Kinase inhibition improves vascular malformations in mouse models of Hereditary Hemorrhagic Telangiectasia. Nat. Commun. 7, 13650, 2016

  6. Baeyens N* Larrivée B* Ola R*, Hayward B, Dubrac A, Huang B, Ross TD, Coon B, Tsarfati M, Tong H, Eichmann A, Schwartz MA. Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia (HHT). J Cell Biol. 214:807-16, 2016 (*BN, LB and OR contributed equally).

CRC1366

European Center for Angioscience

Medical Faculty Mannheim
Heidelberg University

Ludolf-Krehl-Straße 13-17
D-68167 Mannheim

Phone +49 621/383-71450