Felcht,Moritz (3).jpg

Associated Member since 04/21 | Project

Department of Dermatology, Venerology and Allergology

European Center for Angioscience (ECAS)

Medical Faculty Mannheim, Heidelberg University

 

 

moritz.felcht(at)umm.de

Moritz Felcht is a Consultant Physician and runs the Division of Dermatosurgery at the Department of Dermatology, Venereology and Allergology at the University Medical Center Mannheim. Besides, he is the Vice-President of the German Society of Dermatosurgery and PI of the Group Vascular Tumor Microenvironment. He attended the Medical Schools of Freie University of Berlin and Julius-Maximilians University Würzburg and received his M.D. under the supervision of Martin Leverkus at the Department of Dermatology, Julius-Maximilians University Würzburg. He graduated his resident physician training in Dermatology in Mannheim and performed a postdoctoral fellowship at the division of Vascular Oncology and Metastasis at the German Cancer Research Center in Heidelberg.

Qualifications and Scientific Curriculum

2000-2006

2007

2007

2007-2012

2008-2013

since 2013

2013-2015

2015

since 2015

since 2017

2019

since 2020

Medical Degree: Freie University of Berlin and Julius-Maximilians University of Würzburg, Germany with extramural electives in Bristol, UK; Geelong, Australia; Boston and Rochester, USA

Dr. med.

Resident Physician, Department of General and Vascular Surgery, University of Lübeck

Resident Physician, Department of Dermatology, Venereology and Allergology, University Medical Centre Mannheim, Heidelberg University

Postdoctoral fellowship Division of Vascular Oncology and Metastasis at the German Cancer Research Center, Heidelberg

PI of the Research Group Vascular Tumor Microenvironment, Department of Dermatology, Venereology and Allergology, University Medical Centre Mannheim, Heidelberg University

Junior Consultant physician and Sub-Head of the Division of Dermatosurgery, Department of Dermatology, Venereology and Allergology, University Medical Centre Mannheim, Heidelberg University

Venia legendi in Dermatology and Allergology

Consultant Physician and Head of the Division of Dermatosurgery; Department of Dermatology, Venereology and Allergology, University Medical Centre Mannheim, Heidelberg University

Member of the Executive Board of the German Society of Dermatosurgery (DGDC)

Prof. Dr. med.

Managing Chief Physician Department of Dermatology, Venereology and Allergology, University Medical Centre Mannheim, Heidelberg University 

Selected publications

  1. Gengenbacher N*, Singhal M*, Mogler C, Hai L, Milde L, Pari AAA, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa R, Chintharlapalli SR, Augustin HG: Timed Ang2-targeted therapy identifies the Angiopoietin-Tie pathway as key regulator of fatal lymphogenous metastasis. Cancer Discovery. 11:424-45, 2021  (*equal contribution).

  2. Abdul Pari AA, Singhal M, Hübers C, Mogler C, Schieb B, Gampp A, Gengenbacher N, Reynolds LE, Terhardt D, Géraud C, Utikal J, Thomas M, Goerdt S, Hodivala-Dilke KM, Augustin HG*, Felcht M*: Tumor cell-derived Angiopoietin-2 promotes metastasis in melanoma. Cancer Res. 80:2586-96, 2020  (*equal contribution).

  3. Felcht M, Benecke J, Reiners-Koch P: “The Flap Finder”. Springer Medizin https://www.springermedizin.de/ flapfinder, online since Dec. 2020.

  4. Bauer C, Abdul Pari AA, Umansky V, Utikal J, Boukamp P, Augustin HG, Goerdt S, Géraud* C, Felcht M*: T-lymphocyte profiles differ between keratoacanthomas and invasive squamous cell carcinomas of the skin. Cancer Immunol Immunother. 67:1147-57, 2018  (*equal contribution).

  5. Teichert M*, Stumpf C*, Booken N, Wobser M, Nashan D, Hallermann C, Mogler C, Müller CS, Becker JC, Moritz RK, Andrulis M, Nicolay JP, Goerdt S, Thomas M, Klemke CD, Augustin HG, Felcht M: Aggressive primary cutaneous B-cell lymphomas show increased Angiopoietin-2-induced angiogenesis. Exp Dermatol. 24:424-9, 2015  (*equal contribution).

  6. Felcht M, Thomas M: Angiogenesis in malignant melanoma. J Dtsch Dermatol Ges. 13: 125-36, 2015.

  7. Felcht M, Heck M, Weiss C, Becker JC, Dippel E, Müller CS, Nashan D, Sachse MM, Nicolay MP, Booken N, Goerdt S, Klemke CD: Expression of the T-cell regulatory marker FOXP3 in primary cutaneous large B-cell lymphoma tumor cells. Brit J Dermatol. 167:348-58, 2012.

  8. Felcht M, Luck R, Schering A, Seidel P, Srivastava K, Hu J, Bartol A, Kienast Y, Vettel C, Loos EK, Kutschera S, Bartels P, Appak S, Besemfelder E, Terhardt D, Chavakis E, Wieland T, Klein C, Thomas M, Uemura A, Goerdt S, Augustin HG: Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signalling. J Clin Invest. 122:1991-2005, 2012.

  9. Felcht M, N Booken, P Ströbel, S Goerdt, CD Klemke: The value of molecular diagnostics in primary cutaneous B-cell lymphomas in the context of clinic, histology and immunohistochemistry. J Am Acad Dermatol. 25: 788-93, 2011.

  10. Thomas M*, Felcht M*, Kruse K, Kretschmer S, Deppermann C, Biesdorf A, Rohr K, Benest AV, Fiedler U, Augustin HG: Angiopoietin-2 stimulation of endothelial cells ind-uces αvβ3 integrin internalization and degradation. J Biol Chem. 285:23842-9, 2010 (*equal contribution).