Carolin_Mogler.jpg

PD Dr. Carolin Mogler

Project Z2

Institute of Pathology Technical University, Munich

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carolin.mogler(at)tum.de

Carolin Mogler attended Medical School at Heidelberg University. She obtained her MD from Heidelberg University where she investigated heperanase expression on head and neck cancers before she moved on to the Institute of Pathology (Director: Peter Schirmacher) where she got her board certification in surgical pathology 2013. Since 2015 she is consultant pathologist at the Institute of Pathology at the Technical University in Munich, since 2018 managing senior consultant.

Qualifications and Scientific Curriculum

200-2007

2009

2007-2015

2013

2007-2015

since 2015

Medical School, Heidelberg University, Germany

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MD: Institute of Pathology, Heidelberg University, Germany

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Institute of Pathology, Heidelberg University, Germany

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Board certification surgical pathology

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Institute of Pathology, Heidelberg University

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Consultant surgical pathologist, Institute of Pathology, Technical University Munich, Germany

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Managing senior consultant, , Institute of Pathology, Technical University Munich, Germany

since 2018

Selected publications

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  1. Singhal M; Gengenbacher N, Abdul Pari AA, Kamiyama M, Hai L, Kuhn BJ, Kallenberg DM, Kulkarni SR, Camilli C, Preuß SF, Leuchs B, Mogler C, Espinet E, Besemfelder E, Heide D, Heikenwalder M, Sprick MR, Trumpp A, Krijgsveld J, Schlesner M, Hu J, Moss SE, Greenwood J, Augustin HG: Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis. Sci. Transl. Med. 13:eabe6805, 2021.

  2. Heil J, Olsavszky V, Busch K, Klapproth K, de la Torre C, Sticht C, Sandorski K, Hoffmann J, Schönhaber H, Zierow J, Winkler M, Schmid CD, Staniczek T, Daniels DE, Frayne J, Metzgeroth G, Nowak D, Schneider S, Neumaier M, Weyer V, Groden C, Gröne HJ, Richter K, Mogler C, Taketo MM, Schledzewski K, Géraud C, Goerdt S, Koch PS: Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation. Nat Commun. 1:6963, 2021.

  3. Winkler M, Staniczek T, Kürschner SW, Schmid CD, Schönhaber H, Cordero J, Kessler L, Mathes A, Sticht C, Neßling M, Uvarovskii A, Anders S, Zhang XJ, von Figura G, Hartmann D, Mogler C, Dobreva G, Schledzewski K, Géraud C, Koch PS, Goerdt S: Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling. J. Hepatol. 2:380-393, 2021.

  4. Gengenbacher N, Singhal M, Mogler C, Hai L, Milde L, Pari AAA, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa R, Chintharlapalli SR, Augustin HG: Timed Ang2-targeted therapy identifies the angiopoietin-tie pathway as key regulator of fatal lymphogenous metastasis. Cancer Discov. 11:424-445, 2021.

  5. Steiger K, Gross N, Widholz SA, Rad R, Weichert W, Mogler C: Genetically engineered mouse models of liver tumorigenesis reveal a wide histological spectrum of neoplastic and non-neoplastic liver lesions. Cancers. 8:2265-2281, 2020.

  6. Abdul Pari AA, Singhal M, Hübers C, Mogler C, Schieb B, Gampp A, Gengenbacher N, Reynolds LE, Terhardt D, Géraud C, Utikal J, Thomas M, Goerdt S, Hodivala-Dilke KM, Augustin HG, Felcht M: Tumor cell-derived angiopoietin-2 promotes metastasis in melanoma. Cancer Res. 12:2586-2598, 2020.

  7. Mogler C, König C, Wieland M, Runge A, Besemfelder E, Komljenovic D, Longerich T, Schirmacher P, Augustin HG: Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin. EMBO Mol Med. 9:741-749, 2017.

  8.  

    Wieland E, Rodriguez-Vita J, Liebler SS, Mogler C, Moll I, Herberich SE, Espinet E, Herpel E, Menuchin A, Chang-Claude J, Hoffmeister M, Gebhardt C, Brenner H, Trumpp A, Siebel CW, Hecker M, Utikal J, Sprinzak D, Fischer A: Endothelial Notch1 activity facilitates metastasis. Cancer Cell. 31:355-367, 2017.

  9. Mogler C, Wieland M, König C, Hu J, Runge A, Korn C, Besemfelder E, Breitkopf-Heinlein K, Komljenovic D, Dooley S, Schirmacher P, Longerich T, Augustin HG: Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage. EMBO Mol Med, 7:332-8, 2015.

  10. Hu J, Srivastava K, Wieland M, Runge A, Mogler C, Besemfelder E, Terhardt D, Vogel MJ, Cao L, Korn C, Bartels S, Thomas M, Augustin HG: Endothelial cell-derived Angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat. Science, 343:416-9, 2014.