PD Dr. Carolin Mogler
Institute of Pathology Technical University, Munich
carolin.mogler(at)tum.de
Carolin Mogler attended Medical School at Heidelberg University. She obtained her MD from Heidelberg University where she investigated heperanase expression on head and neck cancers before she moved on to the Institute of Pathology (Director: Peter Schirmacher) where she got her board certification in surgical pathology 2013. Since 2015 she is consultant pathologist at the Institute of Pathology at the Technical University in Munich, since 2018 managing senior consultant.
Qualifications and Scientific Curriculum
200-2007
2009
2007-2015
2013
2007-2015
since 2015
Medical School, Heidelberg University, Germany
MD: Institute of Pathology, Heidelberg University, Germany
Institute of Pathology, Heidelberg University, Germany
Board certification surgical pathology
Institute of Pathology, Heidelberg University
Consultant surgical pathologist, Institute of Pathology, Technical University Munich, Germany
Managing senior consultant, , Institute of Pathology, Technical University Munich, Germany
since 2018
Selected publications
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Mogler C, König C, Wieland M, Runge A, Besemfelder E, Komljenovic D, Longerich T, Schirmacher P, Augustin HG: Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin. EMBO Mol Med, 9:741-9, 2017.
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Wieland E, Rodriguez-Vita J, Liebler SS, Mogler C, Moll I, Herberich SE, Espinet E, Herpel E, Menuchin A, Chang-Claude J, Hoffmeister M, Gebhardt C, Brenner H, Trumpp A, Siebel CW, Hecker M, Utikal J, Sprinzak D, Fischer A: Endothelial Notch1 Activity Facilitates Metastasis. Cancer Cell 31:355-67, 2017.
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Viski C, König C, Kijewska M, Mogler C, Isacke CM, Augustin HG: Endosialin-expressing pericytes promote metastatic dissemination. Cancer Res, 76:5313-25, 2016.
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Scholz B, Korn C, Wojtarowicz J, Mogler C, Augustin I, Boutros M, Niehrs C, Augustin HG: Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling. Dev Cell, 36:79-93, 2016.
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Mogler C, Wieland M, König C, Hu J, Runge A, Korn C, Besemfelder E, Breitkopf-Heinlein K, Komljenovic D, Dooley S, Schirmacher P, Longerich T, Augustin HG: Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage. EMBO Mol Med, 7:332-8, 2015.
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Hu J, Srivastava K, Wieland M, Runge A, Mogler C, Besemfelder E, Terhardt D, Vogel MJ, Cao L, Korn C, Bartels S, Thomas M, Augustin HG: Endothelial cell-derived Angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat. Science, 343:416-9, 2014.
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Runge A , Hu J, Wieland M , Bergeest JP, Mogler C, Neumann A, Géraud C, Arnold B, Rohr K, Komljenovic D , Schirmacher P, Goerdt S, Augustin HG: An inducible hepatocellular carcinoma model for preclinical evaluation of anti-angiogenic therapy in adult mice. Cancer Res, 74:4157-69, 2014.
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Horwitz E, Stein I, Andreozzi M, Nemeth J, Shoham A, Pappo O, Schweitzer N, Tornillo L, Kanarek N, Quagliata L, Zreik F, Porat RM, Finkelstein R, Reuter H, Koschny R, Ganten T, Mogler C, Shibolet O, Hess J, Breuhahn K, Grunewald M, Schirmacher P, Vogel A, Terracciano L, Angel P, Ben-Neriah Y, Pikarsky E: Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment. Cancer Discov, 4:730-43, 2014.
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Géraud C, Mogler C, Runge A, Evdokimov K, Lu S, Schledzewski K, Arnold B, Hämmerling G, Koch PS, Breuhahn K, Longerich T, Marx A, Weiss C, Damm F, Schmieder A, Schirmacher P, Augustin HG, Goerdt S: Endothelial transdifferentiation in hepatocellular carcinoma: loss of Stabilin-2 expression in peri-tumourous liver correlates with increased survival. Liver Int, 33:1428-40, 2013.
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Mogler C, Herold-Mende C, Dyckhoff G, Jenetzky E, Beckhove P, Helmke BM: Heparanase expression in head and neck squamous cell carcinomas is associated with reduced proliferation and improved survival. Histopathology, 58:944-52, 2011.