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Prof. Dr. Andreas Fischer

Project C4

Division of Vascular Signaling and Cancer, 

German Cancer Research Center Heidelberg (DKFZ)

Medical Clinic I, Heidelberg University Hospital

European Center for Angioscience (ECAS), 

Medical Faculty Mannheim, Heidelberg University

 

a.fischer(at)dkfz.de

Andreas Fischer is Head of the Division of Vascular Signaling and Cancer at the German Cancer Research Center in Heidelberg. He attended Medical School at the University of Würzburg. As a predoctoral fellow he worked at the Children’s Hospital Boston at Harvard Medical School under the supervision of Stuart Orkin. He pursued postdoctoral research in the laboratory of Manfred Gessler at the Biocenter in Würzburg before he started his own Junior Research Group at the Medical Faculty in Mannheim. Since 2012 he is an independent group leader at the German Cancer Research Center.

Qualifications and Scientific Curriculum

MD, University of Würzburg

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Postdoctoral fellow, Biocenter Würzburg

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Junior group leader, CBTM, Medical Faculty Mannheim. Heidelberg University

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Board certification Physiology

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Independent group leader, German Cancer Research Center Heidelberg

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Adjunct professorship at Heidelberg University

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Clinical practice in laboratory medicine at Heidelberg University Hospital

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Division Head, German Cancer Research Center Heidelberg

2003

2004-2007

2007-2012

2012

2012-2017

2016

since 2014

since 2017

Selected publications

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  1. Mülfarth R, Alsina Sanchis E, Moll I, Bühn S, Stögbauer A, Jorana L, de Angelis Rigotti F, Wiedmann L, Taylor J, Ziegelbauer T, Giaimo T, Borggrefe T, Cerwenka A, Fischer A*, Rodriguez Vita J*: Endothelial Notch-Rbpj signaing regulates macrophage education in ovarian cancer. bioRxiv. (Cancer Res. in revision), 2021. (*Corresponding author)

  2. Hasan SS, Fischer A: Notch signaling in the vasculature: angiogenesis and angiocrine functions. Cold Spring Harb Perspect Med. (accepted for publication) 2022

  3. Weis EM, Puchalska P, Nelson A, Taylor J, Moll I, Hasan SS, Dewenter M, Hagenmueller M, Fleming T, Poschet G, Hotz-Wagenblatt A, Backs J, Crawford P, Fischer A: Ketone body oxidation increases cardiac endothelial cell proliferation. EMBO Mol Med. e14753. 2022.

  4. Alsina-Sanchis E, Mülfarth R, Moll I, Mogler C, Rodriguez-Vita J, Fischer A: Intraperitoneal oil application causes local inflammation with depletion of resident peritoneal macrophages. Mol Cancer Res. 19:288-300, 2021.

  5. Alsina-Sanchis E, Mülfarth R, Fischer A: Control of tumor progression by angiocrine factors. Cancers. 13:2610, 2021.

  6. Morgenstern J, Fleming T, Kliemank E, Brune M, Nawroth P, Fischer A: Quantification of all-trans retinoic acid by liquid chromatography-tandem mass spectrometry and association with lipid profile in patients with Type 2 Diabetes. Metabolites. 11:60, 2021.

  7. Hasan SS, Fischer A: The Endothelium: An active regulator of lipid and glucose homeostasis. Trends Cell Biol. 31:37-49, 2021.

  8. Hubert MO, Rodriguez-Vita J, Wiedmann L, Fischer A: Isolation of murine primary aortic smooth muscle cells. Bio Protoc. 11:e3907, 2021

  9. Hasan SS, Jabs M, Taylor J, Wiedmann L, Leibing T, Nordström V, Federico G, Roma LP, Carlein C, Wolff G, Ekim-Üstünel B, Brune M, Moll I, Tetzlaff F, Gröne HJ, Fleming T, Géraud C, Herzig S, Nawroth PP, Fischer A: Endothelial Notch signaling controls insulin transport in muscle. EMBO Mol Med. 12:e09271, 2020

  10. Klose R, Prinz A, Tetzlaff F, Weis EM, Moll I, Rodriguez-Vita J, Oka C, Korff T, Fischer A: Loss of the serine protease HTRA1 impairs smooth muscle cells maturation. Sci Rep. 9:18224, 2019.

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